Results 271 to 280 of about 1,123,741 (381)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Who is teaching anatomy? An examination of the demographic characteristics, academic backgrounds, and professional responsibilities of US anatomy teachers. [PDF]

Anat Sci Educ
Hall TR, Mosley CF, Vakil JB, Lambert CK, Savelli DM, Balta JY.   +5 more
europepmc   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Retention of gross and clinical anatomy knowledge among medical graduates in Sudan: a comparative study. [PDF]

BMC Med Educ
Saeed M, Ahmed L, AbdAlla E, Alatawi Z, Alhowiti AM, Elmahdi TSA, Mohammed S, Elhag A.   +7 more
europepmc   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Gamification increases medical student confidence in surgical anatomy. [PDF]

Med Educ
Lee R, Kovacs L, Wang J, Lofthouse B, Hughes K.   +4 more
europepmc   +1 more source

The anatomy of the domestic fowl /

, 1918
B.F. KAUPP
openalex   +2 more sources

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Atypical Root Canal System Anatomy in a Permanent Upper First Molar: A Case Report. [PDF]

Cureus
Georgieva S, Borisova-Papancheva T, Zaneva-Hristova D.   +2 more
europepmc   +1 more source

On the Variations of the Internal Anatomy of the Gamasinae, especially in that of the Genital Organs, and on their Mode of Coition.

, 1892
A. D. Michael
openalex   +1 more source