Results 291 to 300 of about 1,123,741 (381)

Enhancing transporter activity in heterologous expression systems with SAHA: a 2500‐times more potent and odorless alternative to butyrate

open access: yesFEBS Open Bio, EarlyView.
Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel   +4 more
wiley   +1 more source

RETRACTION: NGF Protects Neuroblastoma Cells Against β‐Amyloid‐Induced Apoptosis via the Nrf2/HO‐1 pathway

open access: yesFEBS Open Bio, EarlyView.
RETRACTION: R. Su, W. Su, and Q. Jiao, “NGF Protects Neuroblastoma Cells Against β‐Amyloid‐Induced Apoptosis via the Nrf2/HO‐1 pathway,” FEBS Open Bio 9, no. 12 (2019): 2063‐2071, https://doi.org/10.1002/2211‐5463.12742. The above article, published online on 01 November 2019, in Wiley Online Library (wileyonlinelibrary.com), and its correction (https:/
wiley   +1 more source

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

open access: yesFEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

RETRACTION: Effect of a Neural Relay on Liver Regeneration in Mice: Activation of Serotonin Release from the Gastrointestinal Tract

open access: yesFEBS Open Bio, EarlyView.
RETRACTION: R. Inoue, K. Kamimura, T. Nagoya, N. Sakai, T. Yokoo, R. Goto, K. Ogawa, Y. Shinagawa‐Kobayashi, Y. Watanabe‐Mori, A. Sakamaki, S. Abe, H. Kamimura, N. Miyamura, H. Nishina, and S. Terai, “Effect of a Neural Relay on Liver Regeneration in Mice: Activation of Serotonin Release from the Gastrointestinal Tract,” FEBS Open Bio 8, no.
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Anatomical insights and clinical implications of the persistent trigeminal artery: A cadaveric study utilizing latex injection techniques. [PDF]

open access: yesSurg Neurol Int
Reyes Sotos G   +11 more
europepmc   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

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