Results 231 to 240 of about 97,860 (303)

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Dose‐Adjusted Treatment With 7‐Day Venetoclax Plus Azacitidine or Decitabine in Patients With Acute Myeloid Leukaemia

European Journal of Haematology, Volume 117, Issue 5, Page 1358-1368, November 2026.
ABSTRACT Acute myeloid leukaemia (AML) in older or unfit patients is commonly treated with hypomethylating agents (HMA) plus venetoclax (VEN), but prolonged VEN exposure often causes substantial haematological toxicity. We retrospectively analysed 61 elderly AML patients treated with HMA + VEN for 7 (7d), 14 (14d) or > 14 days (> 14d) per cycle.
Laurenz Steiner, Lina S. Silva‐Bermudez, Mahmoud Ghazal, Mohammed Abba, Catharina Gerhards, Georgia Metzgeroth, Alice Fabarius, Stefan Klein, Sebastian Kreil, Nanni Schmitt, Patrick Wuchter, Wolf‐Karsten Hofmann, Alexander Streuer   +12 more
wiley   +1 more source

Exploring the experiences of adolescent primigravidae during their first antenatal care visit in Gauteng Province. [PDF]

S Afr Fam Pract (2004)
Mdakane M, Dlamini X, Ramalepa TN.
europepmc   +1 more source

The Role of Actin‐Filament Bundling Protein, Fimbrin Sac6, and Type‐V Myosin Myo2, in the Motion of the SUN‐Domain Protein, Mps3, During Yeast Meiosis

Genes to Cells, Volume 31, Issue 6, November 2026.
Type‐V myosin (Myo2) promotes the motion of Mps3 patches on the nuclear membrane during yeast meiosis. On the other hand, Sac6 fimbrin, which bundles actin filaments, is not critical for the motion of Mps3, suggesting the role of a few actin filaments in the Mps3 motion.
Shuangping Cheng, Tadasu Nozaki, Yurika Fujita, Masaru Ito, Akira Shinohara   +4 more
wiley   +1 more source

Two-Dose Measles-Containing Vaccine (MCV1 and MCV2) Completion and Associated Factors Among Children Aged 24-59 Months in Soroti City, Uganda: A Cross-Sectional Study. [PDF]

Patient Prefer Adherence
Nyesigye J, Ssekabira AR, Turyasingura E, Namazzi PT, Okello S, Naijuka F, Opito R.   +6 more
europepmc   +1 more source

Mapping wild bee diversity and flower use for an effective conservation of the Doñana biodiversity hotspot

Insect Conservation and Diversity, Volume 19, Issue 6, Page 1603-1619, November 2026.
We compiled the first checklist of wild bees in Doñana Protected Area, documenting 385 species, including three vulnerable and one endangered species listed in the Red List. Bee species exhibit diverse floral preferences, highlighting the need to incorporate plant–pollinator interactions and the role of plants in conservation and management strategies ...
Francisco P. Molina, Nerea Montes‐Pérez, Luis Villagarcía, Ignasi Bartomeus   +3 more
wiley   +1 more source

Estimating the impact and cost-effectiveness of antenatal care approaches in 24 low- and middle-income countries: a modelling study. [PDF]

BMC Glob Public Health
Wulan N, Ten Brink D, Wickramaarachchi T, Ali S, Papageorghiou AT, Scott N.   +5 more
europepmc   +1 more source

Residence-based inequalities in health facility delivery among women in sub-Saharan Africa. [PDF]

Int Health
Aboagye RG, Okyere J, Duodu PA, Wongnaah FG, Ahinkorah BO.   +4 more
europepmc   +1 more source

Determinants of maternal health service utilisation among refugee women in Krisan and Ampain camps, Ghana: <i>a cross-sectional analysis</i>. [PDF]

Front Glob Womens Health
Baatiema L, Ganle JK, Appiah F, Ogaji DS.   +3 more
europepmc   +1 more source