Results 41 to 50 of about 97,860 (303)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Investigations on drone-mounted active noise control

open access: yesActa Acustica
Although drones have many potential applications including parcel delivery and surveillance, their deployment in urban areas is limited by their noise levels.
Steiner Jonas   +2 more
doaj   +1 more source

The Saturne cementless dual‐mobility cup grants satisfactory long‐term survival

open access: yesJournal of Experimental Orthopaedics, 2022
Purpose To report long‐term survival and clinical outcomes of primary total hip arthroplasty (THA) using a Saturne cementless dual‐mobility (DM) cup, and investigate whether patient demographics or surgical parameters affect clinical scores.
Thierry Gaillard   +3 more
doaj   +1 more source

ANC flag

open access: yes, 2023
462.A.5.1(2).pdf created from original election material in the South African Elections Collection held in the Manuscripts Section of the Stellenbosch Library and Information Service.Laminated image of the African National Congress (ANC) emblem and ...

core  

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

ANC-1 functions with mitochondria to polarize ALM axon growth.

open access: yes, 2022
(A) Mutations that disrupt the electron transport chain cause ALM axon polarity defects. (B) Dosage-dependent disruption of ALM axon polarity by Antimycin and Rotenone.
Hongyan Hao (14149843)   +6 more
core   +1 more source

Toward Fit‐for‐Purpose Data for Drug Assessment in Non‐small Cell Lung Cancer: A Core Dataset

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Considering the high unmet medical need in people with non‐small cell lung cancer (NSCLC), the drug assessment for targeted therapies often rely on small populations and single‐arm trials, challenging the evaluation by regulatory authorities, health technology assessment bodies (HTAb), and clinicians.
Geeske F. Grit   +6 more
wiley   +1 more source

Yerevan Brickwork Residential Building Architecture and the Importance of Geographic Information Systems (GIS) in Preservation of Architectural Monuments and Structures

open access: yesJournal of Architectural and Engineering Research
Many buildings were built in Yerevan with bricks. The specifics of brickwork, residential buildings, architecture, and building art in Yerevan have become the subject of the article.
Evlin Ordoukhanian, Shahen Shahinyan
doaj   +1 more source

Coexistence of immunophenotypically normal and aberrant mast cells in patients with clonal mast cell diseases associates with more indolent subtypes and less severe disease characteristics

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky   +6 more
wiley   +1 more source

Entre plumas y colores. Aproximaciones a una mirada cuzqueña sobre la puna salada

open access: yesMemoria Americana, 1996
Qué nombres daban y cómo reconocían los incas a los otros? Esta es la cuestión fundamental que se plantea José Luis Martínez en el presente trabajo.
José Luis Martínez C.
doaj  

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