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Ancestral State Reconstruction of the Apoptosis Machinery in the Common Ancestor of Eukaryotes [PDF]
Apoptotic cell death is a type of eukaryotic cell death. In animals, it regulates development, is involved in cancer suppression, and causes cell death during pathological aging of neuronal cells in neurodegenerative diseases such as Alzheimer’s ...
Roza Kucharczyk +2 more
exaly +7 more sources
Rapid maximum likelihood ancestral state reconstruction of continuous characters: A rerooting‐free algorithm [PDF]
Eric W Goolsby
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Multi-task learning improves ancestral state reconstruction
Theoretical Population Biology, 2019We consider the ancestral state reconstruction problem where we need to infer phenotypes of ancestors using observations from present-day species. For this problem, we propose a multi-task learning method that uses regularized maximum likelihood to estimate the ancestral states of various traits simultaneously.
Lam Si Tung Ho, Vu Dinh, Cuong V Nguyen
exaly +3 more sources
Ancestral State Reconstruction Using BayesTraits
2022The fossil record is the best evidence of the characteristics of extinct species, but only a narrow range of traits fossilize or survive the fossilization process. Lacking fossil or other evidence about the past, ancestral states can be reconstructed. Three pieces of information are combined when reconstructing ancestral states: extant or known trait ...
Andrew, Meade, Mark, Pagel
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When can we reconstruct the ancestral state? A unified theory
Ancestral state reconstruction is one of the most important tasks in evolutionary biology. Conditions under which we can reliably reconstruct the ancestral state have been studied for both discrete and continuous traits. However, the connection between these results is unclear, and it seems that each model needs different conditions.
Lam Si Tung Ho, Vu Dinh
exaly +5 more sources
Ancestral State Reconstruction, Rate Heterogeneity, and the Evolution of Reptile Viviparity [PDF]
Virtually all models for reconstructing ancestral states for discrete characters make the crucial assumption that the trait of interest evolves at a uniform rate across the entire tree. However, this assumption is unlikely to hold in many situations, particularly as ancestral state reconstructions are being performed on increasingly large phylogenies ...
Benedict KING +2 more
exaly +4 more sources
Reconstructing ancestral character states: a critical reappraisal
Trends in Ecology & Evolution, 1998Using parsimony to reconstruct ancestral character states on a phylogenetic tree has become a popular method for testing ecological and evolutionary hypotheses. Despite its popularity, the assumptions and uncertainties of reconstructing the ancestral states of a single character have received less attention than the much less challenging endeavor of ...
C W, Cunningham +2 more
openaire +2 more sources

