Results 31 to 40 of about 1,934 (212)

Human tuberculosis – an ancient disease, as elucidated by ancient microbial biomolecules [PDF]

open access: yesMicrobes and Infection, 2009
Tuberculosis is a major cause of death but infected people with effective immunity may remain healthy for years, suggesting long-term co-existence of host and pathogen. Direct detection and characterisation of ancient microbial DNA and lipid biomarkers confirms palaeopathological diagnoses.
openaire   +3 more sources

Animal helminths in human archaeological remains: a review of zoonoses in the past Helmintos animais em vestígios arqueológicos humanos: revisão de zoonoses no passado

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2009
The authors present a review of records of intestinal parasitic helminths from animals in human archaeological remains, reported since the emergence of paleopathological studies.
Luciana Sianto   +6 more
doaj   +1 more source

La mandragore, non seulement un analgesique narcotique: sa place dans la medecine et la civilisation grecque antique [PDF]

open access: yesArchives of the Balkan Medical Union, 2018
The mandrake, not just a narcotic: its place in medicine and ancient greek civilization Hippocrates and his followers, as well as Pedanius Dioscorides, Pseudo-Galen and Aretaeus of Cappadocia are just a few of the many ancient Greek physicians who ...
Konstantinos LAIOS   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A brief history of the development of infectious disease prevention, control, and biosafety programs in China

open access: yesJournal of Biosafety and Biosecurity, 2020
Safety of human beings has always been threatened by infectious diseases. In the process of fighting them, humans have continuously explored and researched the pathogens, transmission routes, prevention, and curing methods as well as other aspects ...
Liang Huigang   +4 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

open access: yesAdvanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le   +4 more
wiley   +1 more source

Diachronic analysis of major acupoints used in ancient and current acupuncture treatments: Changes in main acupoints over time

open access: yesIntegrative Medicine Research, 2022
Background: Over time, a large body of knowledge on acupoint selection patterns has accumulated. This study compared the main acupoint selection patterns between ancient and current acupuncture treatments.
Yeonjoo Yoo   +3 more
doaj   +1 more source

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