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Beyond binaries. Interrogating ancient DNA

Archaeological Dialogues, 2020
In this paper we explore ancient DNA (aDNA) as a powerful new technique for archaeologists. We argue that for aDNA to reach its full potential we need to carefully consider its theoretical underpinnings.
Rachel J. Crellin, O. Harris
semanticscholar   +1 more source

Ancient DNA analysis

Nature Reviews Methods Primers, 2021
L. Orlando   +10 more
semanticscholar   +1 more source

Ancient DNA

2022
Ancient DNA research—the recovery of genetic material from long-dead organisms—is a discipline that developed from science fiction into a reality between the 1980s and today. Drawing on scientific, historical, and archival material, as well as original interviews with more than fifty researchers worldwide, the book explores the field's formation and ...
openaire   +1 more source

Fishing for ancient DNA

Forensic Science International: Genetics, 2008
The major problems concerning ancient DNA studies are related to the amount of extractable DNA and the precautions needed to avoid contamination. From the very first step of the analyses, the DNA extraction, these problems must be confronted. There are several extraction methods available for DNA in ancient tissue; several of them are complicated and ...
Cecilia, Anderung   +4 more
openaire   +2 more sources

Bone-free ancient DNA

Nature Reviews Genetics, 2021
A new study in Science reports the extraction and analysis of ancient hominid nuclear DNA from Paleolithic sediments. This advance paves the way to a fuller picture of human evolution by bypassing the dependency on rare skeletal remains.
openaire   +2 more sources

Ancient DNA: Methodological challenges

Experientia, 1994
The study of ancient DNA offers the possibility of following genetic change over time. However, the field is plagued by a problem which is unique in molecular biology--the difficulty of verifying results by reproduction. Some of the reasons for this are technical and derive from the low copy number and damaged state of ancient DNA molecules.
Handt, O.   +3 more
openaire   +3 more sources

Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions

Ca-A Cancer Journal for Clinicians, 2021
Michael L Cheng   +2 more
exaly  

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Ancient DNA

2015
DNA studies from highly degraded biological samples that are not preserved in suitable conditions for DNA analyses are called “ancient DNA analyses” Ancient DNA studies may shed light on many scientific issues in parallel with the improvements of the field of molecular biology, however it requires a higher level of sensitivity during applications when ...
İYRAS, H. Merve, DOĞAN, Yeşim
openaire   +1 more source

Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids

Nature Reviews Molecular Cell Biology, 2022
Eva Petermann, Li Lan, Lee Zou
exaly  

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