Results 111 to 120 of about 104,537 (210)

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

Dataset for Single Character Detection in Dongba Manuscripts. [PDF]

open access: yesSci Data
Ma Y   +9 more
europepmc   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho   +2 more
wiley   +1 more source

The Apemen Faces Database (ApeFD). [PDF]

open access: yesSci Data
Lewandowski Z   +6 more
europepmc   +1 more source

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

open access: yesJournal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source

Holocene climate oscillations, seismotectonic events and human–environmental interactions reconstructed from the Giannades palaeolake on Corfu (Eastern Mediterranean, Greece)

open access: yesJournal of Quaternary Science, EarlyView.
ABSTRACT The Mediterranean is particularly sensitive to rapid climate changes (RCCs) during the Holocene. An increasing number of natural climate archives revealed that socio‐economic developments were influenced by such RCCs since the Palaeolithic. However, multi‐millennial and high‐resolution archives are still rare and often located in mountainous ...
Esra Reichert   +7 more
wiley   +1 more source

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