Results 31 to 40 of about 117,744 (259)
Expanding Field-Archaeology Education: The Integration of 3D Technology into Archaeological Training
Open Archaeology, 2021 This contribution analyses and discusses the use of 3D technology in education and learning. Basing the discussion on a case study performed during two seasons of a field school for 1st-year archaeology students, we explore how to expand traditional ...
Derudas Paola, Berggren Åsa
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History of Ancient Pottery [PDF]
, 1873 The Egyptologist Samuel Birch (1813–85) began to study Chinese at school, and obtained his first post at the British Museum cataloguing Chinese coins. He maintained his interest in Chinese civilisation throughout his life, but also collaborated with C. T.
openaire +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Timing the Mesolithic-Neolithic Transition in the Iberian Peninsula: The Radiocarbon Dataset
Journal of Open Archaeology Data, 2019 In this paper, we describe the radiocarbon dataset compiled in the context of the project HAR2015-68962 EVOLPAST: 'Dinámicas evolutivas y patrones de variabilidad cultural de los últimos cazadores-recolectores y el primer Neolítico en el este peninsular (
Salvador Pardo-Gordó +3 more
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Theoretical Roman Archaeology Journal, 2022 Over the last few decades, a critical revision of prior scholarship concerning Roman domestic space has led to the reappraisal of the traditional account of the atrium suggesting a possibility for this space to be ‘unroofed’.
Danilo Marco Campanaro
doaj +2 more sources
Advanced Materials Interfaces, EarlyView.Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source