Results 41 to 50 of about 33,738 (266)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

A Market Assessment of Distributed Battery Energy Storage to Facilitate Higher Renewable Penetration in an Isolated Power System

IEEE Access, 2022
Power systems with a high share of renewables require additional ancillary services to operate safely and reliably. System operators are introducing schemes to attract investment in technology which will provide ancillary services.
Neil McIlwaine, Aoife M. Foley, Dlzar Al Kez, Robert Best, Xi Lu, Chongyu Zhang   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Assessing the Scalability and Privacy of Energy Communities by Using a Large-Scale Distributed and Parallel Real-Time Optimization

IEEE Access, 2022
In the context of the energy transition, energy communities are gaining increasing attention all over the world, in recent years. By participating in an energy community, prosumers may take a leading role in the energy transition and improve the self ...
Mohammad Dolatabadi, Pierluigi Siano, Alireza Soroudi   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Co-optimising frequency-containment services from zero-carbon sources in electricity grids dominated by Renewable Energy Sources

International Journal of Electrical Power & Energy Systems
Power systems dominated by Renewable Energy Sources (RES) are characterised by reduced levels of inertia, which in turn threaten the security of the electricity grid, and significantly increase the requirement for ancillary services such as inertia and ...
Aimon Mirza Baig, Luis Badesa, Yi Wang, Goran Strbac   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Ancillary services and consumerism in India: comparative perspectives on renewable markets

Academia Green Energy
Ancillary services are an integral part to support challenges such as intermittent generation, risk, and large-scale (LS) integration of renewable energy sources (RESs). New changing environments, such as system response and variation, as well
Vivek Soni, Vedansh Verma
doaj   +1 more source

Dynamic wake analysis of a wind turbine providing frequency support services

IET Renewable Power Generation, 2022
The participation of wind farms in providing ancillary services is an asset for the power system and one way to maintain a strong grid with the increasing penetration of renewable energy sources.
Narender Singh, Jeroen D. M. De Kooning, Lieven Vandevelde   +2 more
doaj   +1 more source