Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Interdisciplinary approach in post-cardiac arrest anoxic brain injury with unconfirmed brain death. [PDF]
Abdelrehim A +3 more
europepmc +1 more source
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source
Deep learning models accurately predict cervical lymph node metastasis and key genetic mutations (BRAF/TERT) directly from thyroid cancer frozen sections. This AI‐driven pipeline provides a rapid real‐time tool to guide intraoperative surgical decisions, helping to optimize surgical extent and prevent both over‐ and under‐treatment without the need for
Mingxing Qiu +20 more
wiley +1 more source
The Importance of the Interventional Pathologist in Fine Needle Aspiration and Core Needle Biopsy Procedures for Lymph Node Lesions: A Retrospective Analysis of Diagnostic Correlation and Proposal of a Classification System for Lymph Node Core Needle Biopsies. [PDF]
de la Torre Serrano M +9 more
europepmc +1 more source
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
Localizing Nerve Injury, Defining Injury Severity, and Estimating Prognosis (Nerve SPACE 2025). [PDF]
Fowler J +10 more
europepmc +1 more source
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen +6 more
wiley +1 more source
Unmasking Wilson's Disease Through Severe Psychiatric Manifestations: A Case Report. [PDF]
Dias F +6 more
europepmc +1 more source
ABSTRACT This article identifies assistive technologies (ATs) as ‘pre‐technologies’ mediating access to other technologies for disabled subjects (DSs). The motivation is to show that without ATs, DSs cannot be said to have the same level of access to freedom and self‐forming activities as able‐bodied subjects.
Sarel Marais
wiley +1 more source

