Results 181 to 190 of about 2,892,099 (199)

Whole body analysis of functional communities and topological features of gait with different speeds in Parkinson's disease. [PDF]

J Neurol
Saegner K, Conceição P, Romijnders R, Welzel J, Vuillerme N, Hansen C, Warmerdam E, Maetzler W.   +7 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Examining bidirectional longitudinal relationships between physical activity and physical function in older breast cancer survivors: The Thinking and Living with Cancer study. [PDF]

Cancer
Artese AL, Zhou X, Small BJ, Ahles TA, Ahn J, Bethea TN, Casagrande CC, Choi E, Cohen HJ, Extermann M, Graham D, Hall K, Isaacs C, Jim HSL, Kusters CDJ, McDonald BC, Nakamura ZM, Patel SK, Rentscher KE, Root JC, Saykin AJ, Van Dyk K, Zhai W, Carroll JE, Mandelblatt J.   +24 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Type I hair cells of striolar and central zones in vestibular organs are essential for head stability and postural control. [PDF]

Proc Natl Acad Sci U S A
Ono K, Lee HJ, Chang HHV, Verdone BM, Wafa T, Ji Y, Huang A, Fitzgerald T, Cullen KE, Wu DK.   +9 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Beyond recovery: long-term cardiovascular risks after severe COVID-19 requiring intensive care. [PDF]

Crit Care
Kämpe J, Jonson M, Rubenson Wahlin R, Hollenberg J, Svensson P, Nordberg P.   +5 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Design of an artificial intelligence model to screen spontaneous speech to detect Alzheimer's Disease. [PDF]

PLOS Digit Health
Madden KM, Feldman B, Jimenez D, Khokhar M, Li Q, Nguyen M, Zhu J.   +6 more
europepmc   +1 more source

Cerebrospinal Fluid Cytokine and Chemokine Profiles in Autoimmune Encephalitis: A Cross-sectional Study. [PDF]

Ann Neurosci
Srivastava A, Singh RK, Banerjee J, A E, Das A, Ramanujam B, Parihar J, Pandit AK, V Y V, Vibha D, Chandra S, Srivastava MVP, Tripathi M.   +12 more
europepmc   +1 more source