Results 121 to 130 of about 10,683,434 (298)
Boston University School of Medicine catalog [PDF]
, 1886 Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Gynecology Obstetrics & Reproductive Medicine, 2021 Gynecology Obstetrics and Reproductive Medicine
doaj
Arthroscopy TechniquesAnterior cruciate ligament (ACL) ganglion cysts and mucoid degeneration of the ACL are 2 distinct nontraumatic lesions of the ACL that occur discretely but can coexist. The exact etiopathogenesis still needs to be clarified.
Milind V. Pimprikar, M.S. D. Orthopaedics, P.G.Dip. Sports and Exercise Medicine (UK) +1 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Boston University School of Medicine catalog
, 1891 Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Boston University School of Medicine catalog [PDF]
, 1882 Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Boston University School of Medicine catalog [PDF]
, 1904 Course catalog and informational material for the Boston University School of ...
Boston University School of Medicine
core