Results 241 to 250 of about 8,489,039 (291)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Incidence, Risk Factors, and Reasons for Emergency Department Utilization 90 Days After Achilles Tendon Repair. [PDF]

Orthop J Sports Med
Holle AM, Lin E, Driggs A, Tummala SV, Patel K.   +4 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Factors and determinants of primary care to tertiary care referrals in Singapore: A multi-centre analysis using artificial intelligence-powered large language models. [PDF]

PLoS One
Koh SWC, Huang JYX, Lam J, Low SH, Goh JC, Ji G, Jin X, Bauchner H, Lew YJ.   +8 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Dental Treatment Discontinuation for Financial Reasons Among Patients with Cancer: A Cross-Sectional Study with Non-Cancer Controls. [PDF]

J Clin Med
Lee K.
europepmc   +1 more source

Reasons for unplanned hospitalisation in specialist community palliative care: a scoping review. [PDF]

BMC Palliat Care
Elvidge N, Carter HE, Rolfe M, Smith K, Phillips JL.   +4 more
europepmc   +1 more source

Punshon\u27s Reasons for Hope: The Faith and Future of the Friends Church - Book Review

, 2014
Gwyn, Douglas
core  

Comparison of the Number and Reasons for Self-Perceived Barriers to Accessing Primary Health Care Services Between Roma and Ethnic Albanians. [PDF]

Zdr Varst
Naum A, Gjyzari A, Qirjako G, Czabanowska K, Toçi E, Burazeri G.   +5 more
europepmc   +1 more source