Results 71 to 80 of about 2,297,477 (268)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

NUMBER AND COMPOSITION OF PRISONERS IN PRISONS OF ANTI-BOLSHEVIK GOVERNMENTS IN EASTERN SIBERIA (1918 – 1919)

open access: yesВестник Кемеровского государственного университета, 2014
The paper analyzes the topical issueof the number of prisoners in prisons of anti-Bolshevik regimes in Eastern Siberia. The authors believe that the evaluations of Soviet historians were clearly overestimating.
S. P. Zvyagin, I. M. Likstanov
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

أسباب النزول وأثرها في تفسير التحرير والتنوير للطاهر بن عاشور «دراسة نظرية تطبيقية» [PDF]

open access: yesMağallaẗ Kulliyyaẗ al-dirāsāt al-islāmiyyaẗ wa al-ʿarabiyyaẗ lil banat bi ğāmiʿaẗ Al-Ahzhar farʿ kafr Al-Sheikh
يسلط هذا البحث الضوء على قضية أسباب النزول وأثرها في تفسير التحرير والتنوير للطاهر بن عاشور، ويهدف البحث إلى بيان مفهوم أسباب النزول عند ابن عاشور والضوابط التي وضعها لمعرفة سبب النزول وتحديده، وكذلك بيان موقفه من بعض القضايا المتعلقة بأسباب النزول، كما ...
محمد عبد الوهاب الراسخ
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

CONTEMPORARY SACRED ART – REFLECTIONS ON ITS ESSENCE AND REASONS FOR CONCERN

open access: yesSacrum et Decorum, 2009
The text aims to show the crucial relationship between the creative process of an architect and artist, who undertakes a project for a church and for the Church, and his spiritual life and his faith.
Stanisław Rodziński
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Reasons for Choosing Teacher Education and Influence of Peers: A Test of Mediating Effect of Self- determination among Teacher Education Students

open access: yesInternational Journal of Multidisciplinary Educational Research and Innovation
This study aims to determine the mediating effect of self-determination on the relationship between peer influence and reasons for choosing teacher education among first-year education students at Kapalong College of Agriculture, Sciences and Technology.
Abrielle Kylle P. Naciongayo   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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