Results 131 to 140 of about 62,368,048 (338)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Internet of things: Vision, applications and research challenges

open access: yesAd hoc networks, 2012
D. Miorandi   +3 more
semanticscholar   +1 more source

Lingnan Gardeners Newsletter (No. 33) = 嶺南彩園通訊 (第33期)

open access: yes, 2017
Flowers of Dragon Fruit 火龍果花https://commons.ln.edu.hk/ln_gardeners_newsletter/1033/thumbnail ...
Lingnan Gardeners, Kwan Fong Cultural Research and Development Programme, Lingnan University
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lingnan Gardeners Bimonthly Newsletter (No. 47) = 嶺南彩園通訊 (第47期)

open access: yes, 2019
Balsamines 鳳仙花https://commons.ln.edu.hk/ln_gardeners_newsletter/1047/thumbnail ...
Lingnan Gardeners, Kwan Fong Cultural Research and Development Programme, Lingnan University
core   +2 more sources

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