Results 181 to 190 of about 3,961,089 (355)

Utilizing Biomarkers, CRP and Ferritin, to Predict the Development of Cytokine Release Syndrome in Patients Receiving Chimeric Antigen Receptor Cell Therapy

open access: hybrid, 2023
Juhi Gor   +6 more
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Detection of colinear blocks, and synteny and evolutionary analyses based on utilization of MCScanX

open access: green, 2023
Yupeng Wang   +5 more
openalex   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Characterizing the Use of Home-Based Behavioral Health Services Among Children in Foster Care. [PDF]

open access: yesChild Youth Serv Rev
Chorniy A   +4 more
europepmc   +1 more source

Correction: Surgical Utilization and Outcomes for Patients with Stage IV Melanoma in the Modern Immunotherapy Era [PDF]

open access: bronze
Thinzar M. Lwin   +4 more
openalex   +1 more source

Sporadic utilization of ITN among households with under-five HIV positive children [PDF]

open access: green, 2019
David Ayah Ounah   +6 more
openalex   +1 more source

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