ChemMedChem, Volume 21, Issue 5, 13 March 2026.This study explores the development of dual‐acting compounds combining σ1R agonists and histone deacetylase inhibitors (HDACi). Key findings include compound 2d and 3a's high affinity for σ1R and favorable pharmacokinetic profile and an in vivo determined σ1R agonist profile by reversing the effect of the σ1R antagonist BD‐1063.
Antonino N. Fallica +16 more
wiley +1 more source
Accessibility of healthcare services for seasonal migrant farmworkers in Spain: barriers and facilitators identified by professionals. [PDF]
J Migr Healthvan Selm L +6 more
europepmc +1 more source
, 2011 La revista coreana C3 publica el Museo de la Memoria de Andalucía. Contiene textos, imágenes, planos y dibujos del autor. El Museo de la Memoria se centra en la investigación de distintos modos de relacionarse la materia y el aire. Yuxtapone volúmenes de masa y vacío creando tensiones duales y complementarias.
openaire +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, Volume 20, Issue 3, Page 850-862, March 2026.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Do's and Don'ts When Visiting Circularly Polarized Luminescence
Advanced Optical Materials, Volume 14, Issue 11, 20 March 2026.This perspective presents our insights into the principles, challenges, and opportunities of circularly polarized luminescence (CPL). Highlighting key concepts such as the dissymmetry factor (glum) and molecular design strategies, we discuss advances in CPL efficiency, emerging NIR emitters, solid‐state applications, and the growing role of theory and ...
Rafael G. Uceda +9 more
wiley +1 more source
Further insights into maternal and paternal human histories in southern Iberia. [PDF]
Evol Hum SciGonzález-Barrio M +3 more
europepmc +1 more source
In vivo mapping of cortical amyloid beta‐myelin coupling in preclinical Alzheimer's disease
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract INTRODUCTION Accumulating evidence suggests that amyloid‐β (Aβ) preferentially deposits in poorly myelinated cortical regions and may interfere with remyelination. We hypothesized that this vulnerability would manifest as altered Aβ–myelin coupling in preclinical Alzheimer's disease (AD).
Mercedes Atienza, Jose L. Cantero
wiley +1 more source
Ten years of data on small mammal species in Doñana (SW Spain): 2011-2021. [PDF]
Biodivers Data JCarro F +9 more
europepmc +1 more source
AI Hallucinations in Tourism: How Errors Impact Consumer Trust and Recommendation Acceptance
Journal of Consumer Behaviour, Volume 25, Issue 2, Page 923-938, March 2026.ABSTRACT Generative artificial intelligence (GenAI) is quickly transforming travel planning; however, its outputs can include hallucinations, which are plausible yet false statements that can undermine user judgement. Eliminating hallucinations in GenAI technology is currently impossible.
Francisco Rejón‐Guardia +2 more
wiley +1 more source
Ecology and distribution of the recently discovered ked Lipoptena andaluciensis (Diptera: Hippoboscidae) in Spain. [PDF]
Sci RepGonzález MA +4 more
europepmc +1 more source