Results 31 to 40 of about 69,247 (296)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

An in-depth analysis of data reduction methods for sustainable deep learning [version 2; peer review: 2 approved]

open access: yesOpen Research Europe
In recent years, deep learning has gained popularity for its ability to solve complex classification tasks. It provides increasingly better results thanks to the development of more accurate models, the availability of huge volumes of data and the ...
Matteo Rucco   +5 more
doaj   +1 more source

PERTANGGUNGJAWABAN PIDANA KASUS PELAJAR YANG MENINGGAL AKIBAT MENGIKUTI MASA ORIENTASI SISWA [PDF]

open access: yes, 2016
Pada Pasal 351 Kitab Undang-undang Hukum Pidana ayat 3 disebutkan jikapenganiayaan menyebabkan mati diancam pidana penjara paling lama tujuh tahun.Dan Pasal 359 Kitab Undang-undang Hukum Pidana menyebutkan barang siapakarena kelalaiannya( kealpaannya ...
MOHD ANDALUSIA MASRI
core  

Explanatory factors of university student participation in flamenco [PDF]

open access: yes, 2019
The present work offers a study exploring University of Seville students’ cultural participation and how often they attend live flamenco shows. Based on the statistical yearbook of this university, a sample of 452 students from different fields was ...
Oliver Alfonso, María Dolores   +2 more
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

İbnü’l-Cezerî’nin (ö. 833/1429) Müncidü’l-Muḳriîn Adlı Eserinin Endülüs Kıraat Ekolü Açısından Kaynak Değeri

open access: yesHitit İlahiyat Dergisi, 2022
Endülüs, Doğu İslâm coğrafyasındaki karışıklıklar sebebiyle bilhassa hicrî beşinci ve altıncı asırlarda kıraat sahasının öne çıkan bölgelerinden biri olmuştur.
Abdulhalim Başal
doaj   +1 more source

Historical SDI, thematic maps and analysis of a complex network of medieval towers (13th-15th century) in the moorish strip [PDF]

open access: yes, 2018
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Volume XLII-4, 2018 ISPRS TC IV Mid-term Symposium “3D Spatial Information Science – The Engine of Change”, 1–5 October 2018, Delft, The NetherlandsThis ...
Ferreira Lopes, Patricia   +1 more
core   +2 more sources

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez   +5 more
wiley   +1 more source

Unicanvas: Exploring a tool for strategic management [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesOpen Research Europe
Purpose This research proposes an adapted version of Business Model Canvas (BMC) as a strategic instrument for Higher Education Institutions (HEIs). University-Model Canvas (Unicanvas) is intended to be a critical visual and dynamic tool for addressing ...
Mariluz Fernandez-Alles   +3 more
doaj   +1 more source

Energy Assessment of Pastoral Dairy Goat Husbandry from an Agroecological Economics Perspective. A Case Study in Andalusia (Spain) [PDF]

open access: yes, 2018
This paper presents a methodological proposal of new energy sustainability indicators according to a novel accounting that follows agroecological and ecological economics criteria.
Gutiérrez Peña, Rosario   +3 more
core   +1 more source

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