Results 261 to 270 of about 35,890 (290)

Testicular feminization syndrome (Androgen insensitivity)

Journal of Pediatric Surgery, 1981
Three children with testicular feminization syndrome have been seen in the past 4 yr. Each presented with at least one large inguinal hernia. The gonad was proven to be a testis by frozen section. Gonadectomy and herniorrhaphy were done. The plan is to remove the second gonad after puberty.
Donald G. Marshall, G. Howard Valentine
openaire   +4 more sources

Complete Androgen Insensitivity Syndrome—A Review

Journal of Pediatric and Adolescent Gynecology, 2008
This review paper highlights important diagnostic and therapeutic concerns for girls with Complete Androgen Insensitivity Syndrome (CAIS). CAIS is an androgen receptor defect disorder associated with vaginal and uterine agenesis in women with a 46,XY karyotype.
Aimee D. Eyvazzadeh, Meghan B. Oakes, Elisabeth H. Quint, Yolanda R. Smith   +3 more
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Imaging characteristics of androgen insensitivity syndrome

Clinical Imaging, 2015
Androgen insensitivity syndrome (AIS), also known as testicular feminization, is a genetic disorder which leads to lack of response to androgens caused by a defect in the androgen receptor. It is relatively uncommon and is usually diagnosed through clinical symptoms, laboratory findings, physical exam, radiological imaging, and genetic analysis.
Jay Tank, Susanne Kim, Abraham Knoll, Anthony Gilet   +3 more
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Complete Androgen Insensitivity Syndrome

2021
In this chapter, the clinical features, diagnosis, and treatment of complete androgen insensitivity syndrome (CAIS) are presented. CAIS is a rare disease belonging to the disorders of sex development (DSD), which is a cause for primary amenorrhea in women.
Blazej Meczekalski, Agnieszka Podfigurna, Anna Szeliga, Monika Grymowicz, Roman Smolarczyk, Katarzyna Smolarczyk, Ewa Rudnicka   +6 more
openaire   +2 more sources

Human Androgen Insensitivity Syndrome

Journal of Andrology, 1995
The clinical and pathophysiologic features of AIS provide a human model for understanding the role of androgen and its receptor in the induction and maintenance of male sex differentiation and function. Upon inspection, one is immediately impressed by the diverse nature of the mutations involved in the spectrum of AIS and the heterogeneous distribution
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The subcellular defects in the androgen insensitivity syndrome

Acta Endocrinologica, 1986
ABSTRACT The androgen insensitivity syndrome (AIS) was studied with consideration of the complexity of mechanisms involved on the intracellular level: testosterone (T) and dihydrotestosterone (DHT) receptors and the androgen-5α-reductase (A5R).
W. Swoboda, K. Herkner
openaire   +3 more sources

8 Androgen insensitivity syndrome

Baillière's Clinical Endocrinology and Metabolism, 1994
Summary In a relatively short period of time, understanding of the fundamental causes of androgen insensitivity syndromes has improved dramatically. This has been brought about by the combination of several disciplines, including endocrinology, genetics, developmental and molecular biology. Mutations can be identified in the androgen receptor gene in
Michael J. McPhaul, Ieuan A. Hughes, Mark Patterson   +2 more
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Testicular feminization: The androgen insensitivity syndrome

Journal of Pediatric Surgery, 1992
Testicular feminization (TF) is a syndrome due to androgen insensitivity. It occurs in a complete (CTF) and an incomplete (ITF) form. We have treated 21 patients with TF over the last 24 years. Eight patients presented because of ambiguous genitalia, seven presented as "females" with inguinal hernia and testes were found at surgery, five were diagnosed
Morton M. Woolley, Rajkumar Shah, Gertrude Costin   +2 more
openaire   +3 more sources

A Clinical Syndrome of Mild Androgen Insensitivity*

The Journal of Clinical Endocrinology & Metabolism, 1984
We studied four patients from three kindreds who had normal male body habitus and external genitalia except for short penile length and gynecomastia. Prostate size was small in all patients and spermatogenesis was decreased markedly in one and absent in three.
Edgar J. Schoen, Anselmo Palacios, Roberto Lanes, Terry R. Brown, Claude J. Migeon, James A. Amrhein   +5 more
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Osteopenia as a feature of the androgen insensitivity syndrome

Clinical Endocrinology, 1995
SummaryOBJECTIVE The syndrome of androgen insensitivity, a paradigm of a hormone resistance syndrome, manifests as failure of masculinization despite normal or high concentrations of serum testosterone. The defect in these 46 XY patients resides in the androgen receptor gene, with consequent defective androgen action and abnormal sexual differentiation.
Howard S. Jacobs, Gordana M. Prelevic, Gordana M. Prelevic, Steven Soule, Jean Ginsburg, Gerard S. Conway, Malcolm Prentice   +6 more
openaire   +3 more sources