Results 301 to 310 of about 238,876 (343)
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Maturitas, 2007
Steroids arriving from the gonads via the circulation modulate brain function, affecting gender differentiation and sexually differentiated behavioral responses, but also the ability of the brain to process, store and retrieve sensory information. Androgens play a pivotal neuroactive role during the "organizational/developmental" phase, mainly in the ...
GENAZZANI, ANDREA +4 more
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Steroids arriving from the gonads via the circulation modulate brain function, affecting gender differentiation and sexually differentiated behavioral responses, but also the ability of the brain to process, store and retrieve sensory information. Androgens play a pivotal neuroactive role during the "organizational/developmental" phase, mainly in the ...
GENAZZANI, ANDREA +4 more
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Androgens, Antiandrogens and Androgen Receptor Abnormalities
European Urology, 1996Information on the molecular structure of the human androgen receptor has increased insight into the molecular mechanism of action of androgens and antiandrogens. It has also facilitated the study of molecular defects in the androgen receptor gene associated with prostate cancer.
A O Brinkmann, C W Kuil
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Androgens and androgen receptors in breast cancer
The Journal of Steroid Biochemistry and Molecular Biology, 2007Aromatase (CYP19) converts adrenal and ovarian androgens into estrogens, which supports the growth of estrogen-dependent breast cancers. Anti-aromatase agents are displacing antiestrogens as the first-line treatment for estrogen receptor positive breast cancers.
Juan C. Díaz-Chico +9 more
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2016
Androgen abuse is the most potent and prevalent form of sports doping detected. It originated from the early years of the Cold War as an epidemic confined to drug cheating within elite power sports. In the decades following the end of the Cold War, it has become disseminated into an endemic based within the illicit drug subcultures serving recreational
Rakesh Iyer, David J. Handelsman
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Androgen abuse is the most potent and prevalent form of sports doping detected. It originated from the early years of the Cold War as an epidemic confined to drug cheating within elite power sports. In the decades following the end of the Cold War, it has become disseminated into an endemic based within the illicit drug subcultures serving recreational
Rakesh Iyer, David J. Handelsman
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Androgen antagonists in androgen target tissues
Pharmacology & Therapeutics, 1984Most antiandrogens appear to act by binding to the androgen receptor and competitively inhibiting the binding of testosterone and cihydrotestosterone to the receptor. Focusing on those compounds which appear to inhibit androgen receptor mediated responses this review discusses the chemistry of those antiandrogens which have been studied to the extent ...
C.H. Chang +7 more
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Andrologia, 2000
Androgen receptors are present in relevant numbers in osteoblasts. Stimulation of androgen receptors in osteoblastic bone marrow stromal cells inhibits the differentiation of osteoclasts in the bone marrow cavity. Androgens not only inhibit osteoclastogenesis but also increase cortical bone formation mainly by stimulating periosteal bone formation ...
Dirk Vanderschueren, Liesbeth Vandenput
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Androgen receptors are present in relevant numbers in osteoblasts. Stimulation of androgen receptors in osteoblastic bone marrow stromal cells inhibits the differentiation of osteoclasts in the bone marrow cavity. Androgens not only inhibit osteoclastogenesis but also increase cortical bone formation mainly by stimulating periosteal bone formation ...
Dirk Vanderschueren, Liesbeth Vandenput
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Androgens, Anabolic-Androgenic Steroids, and Inhibitors
American Journal of Therapeutics, 2000Androgens are steroid hormones responsible for male sexual characteristics, testosterone being the principal androgen secreted by the testes. Androgens have both masculinizing and growth-stimulating or anabolic effects. Synthetic analogs of androgens have been used by professional, as well as amateur, athletes for possible performance enhancement.
David T. Lowenthal, James L. Donahue
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Androgen receptor mutations and androgen insensitivity
Molecular and Cellular Endocrinology, 2002The androgen receptor (AR) is a high affinity receptor protein encoded on the human X-chromosome that mediates the actions of androgens during development and in the adult. Defects in this receptor protein result in a wide range of abnormalities of male sexual development.
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Androgens and Anti-androgen Therapy
Archives of Dermatology, 1984One's first thoughts about a book on androgens and antiandrogens would likely be that it would contain some reference to the skin and that much of the text would be devoted to discussions on hormones and their relevance to other organ systems. Actually, that is not the case here.
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Endocrinology, 1981
Tritiated dihydrotestosterone ([3H]DHT) binds with high affinity to a single class of limited capacity sites in cytoplasmic preparations from rat and mouse thymus glands. The affinity of these bindings sites for [3H]DHT (Kd at 4 C, 1 nM) and their specificity [methyltrienolone (R1881) greater than DHT greater than testosterone much greater than ...
Paul Pearce +2 more
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Tritiated dihydrotestosterone ([3H]DHT) binds with high affinity to a single class of limited capacity sites in cytoplasmic preparations from rat and mouse thymus glands. The affinity of these bindings sites for [3H]DHT (Kd at 4 C, 1 nM) and their specificity [methyltrienolone (R1881) greater than DHT greater than testosterone much greater than ...
Paul Pearce +2 more
openaire +3 more sources