Phenotype-based profiling of female sexual function in pregnancy: a cross-sectional study [PDF]
Frontiers in EndocrinologyIntroductionSexual function during pregnancy is commonly described in terms of overall decline or sexual dysfunction prevalence, potentially overlooking heterogeneity across individual domains.
Roberta Scairati +11 more
doaj +2 more sources
Tirzepatide as a therapeutic tool for kidney impairment in obesity: insights from a real-world study [PDF]
Journal of Translational MedicineBackground Obesity is a major risk factor for chronic kidney disease (CKD), contributing to kidney dysfunction through metabolic alterations and chronic inflammation.
Martina Galasso +7 more
doaj +2 more sources
Very low energy ketogenic therapy: an anti-inflammatory medical nutritional approach for MASLD in obesity [PDF]
Journal of Translational MedicineBackground Chronic inflammation, oxidative stress, and high CRP are linked to metabolic dysfunction-associated steatotic liver disease (MASLD); Very low energy ketogenic therapy (VLEKT) shows anti-inflammatory effects in obesity.
Luigi Barrea +5 more
doaj +2 more sources
Tirzepatide and metabolic dysfunction-associated steatotic liver disease (MASLD) in obesity: a real-world multicenter study [PDF]
Frontiers in EndocrinologyIntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and is strongly associated with obesity, insulin resistance, and systemic inflammation.
Martina Galasso +13 more
doaj +2 more sources
Sex differences in classic congenital adrenal hyperplasia: a multicenter, real-world analysis [PDF]
Frontiers in EndocrinologyBackgroundThe phenotypic variability of classic congenital adrenal hyperplasia (CAH) demands tailored management to optimize disease control and attenuate long-term consequences. Although sex-specific differences have been recognized, real-world evidence
Chiara Simeoli +12 more
doaj +2 more sources
Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy (VLEKT) in Women with Obesity [PDF]
MetabolitesBackground/Objectives: Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite increasingly recognized as a pro-atherogenic factor and a biomarker of cardiometabolic risk. Dietary patterns and adiposity are key modulators of circulating TMAO
Giuseppe Annunziata +10 more
doaj +2 more sources
Differential impact of coffee quantity and sweetening on body composition parameters and inflammation [PDF]
Frontiers in NutritionBackgroundCoffee is the most consumed and popular beverage worldwide. The health benefits of its regular, moderate consumption are well known, and include antioxidant and anti-inflammatory effects, as well as metabolic effects, reducing the risk of ...
Giuseppe Annunziata +18 more
doaj +2 more sources
The night matters: sleep quality and evening chronotype associated with clinical severity of psoriasis [PDF]
Frontiers in EndocrinologyIntroductionPsoriasis is a chronic inflammatory skin disease associated with metabolic dysfunction and obesity. Poor sleep quality appears more prevalent in psoriasis, yet the role of chronotype remains largely unexplored.
Ludovica Verde +15 more
doaj +2 more sources
Diagnostic delay length and disease severity are the main predictors of sleep apnea in acromegaly patients [PDF]
Frontiers in EndocrinologyContextObstructive sleep apnea (OSA) affects up to 80% of patients at diagnosis of acromegaly and often persists despite treatment. Currently, patients at risk for OSA are recommended to be identified to offer polygraphy evaluation.PurposeTo study the ...
Rosa Pirchio +13 more
doaj +2 more sources
Editorial: Environmental exposomics and metabolic disorders [PDF]
Frontiers in Endocrinology, 2023 Luana Ricci Paulesu +4 more
doaj +2 more sources