Results 11 to 20 of about 62 (57)

Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)

Drug Testing and Analysis, Volume 18, Issue 3, Page 341-353, March 2026.
As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper, Gregor Fusshöller, Mario Thevis   +2 more
wiley   +1 more source

Detection of a Single Microdose of Testosterone and Recombinant EPO in Healthy Volunteers

Drug Testing and Analysis, Volume 17, Issue 11, Page 2220-2227, November 2025.
Exogenous T was detected with IRMS regardless of T/E elevation—high serum T indicative for IRMS. rhEPO was detected in urine for 72 h in ITP and CP, and Tasso showed less sensitivity than previous DBS devices tested. ABSTRACT Doping with testosterone (T) and erythropoietin (EPO) in low doses (micro‐doping) is a challenge to detect.
Carmel Heiland, Oscar Hopcraft, Mats Johanson, Anton Pohanka, Mikael Lehtihet, Lena Ekström   +5 more
wiley   +1 more source

Humoral Pathway for Local Transfer of the Priming Pheromone Androstenol from the Nasal Cavity to the Brain and Hypophysis in Anaesthetized Gilts [PDF]

Experimental Physiology, 2000
It is generally accepted that pheromones act by stimulating of the dendritic receptors of the olfactory neurones massed in the olfactory epithelium. This study was designed to ascertain whether it is possible for the boar pheromone androstenol (5alpha‐androst‐16‐en‐3‐ol) to be transported from the nasal cavity of anaesthetized gilts to the brain and ...
S, Stefańczyk-Krzymowska, T, Krzymowski, W, Grzegorzewski, B, W sowska, J, Skipor   +4 more
openaire   +2 more sources

Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt‐Foxo1 Pathway

Advanced Science, Volume 11, Issue 43, November 20, 2024.
This study highlights the role of the constitutive androstane receptor (Car), a receptor of endo and xeno‐biotics, in testicular pathophysiology. The results indicate that Car inhibition impaired male fertility due to altered sperm quality, specifically histone retention, which is correlated with offspring's survival. This work demonstrates that Car is
Mélusine Monrose, Hélène Holota, Guillaume Martinez, Christelle Damon‐Soubeyrand, Laura Thirouard, Emmanuelle Martinot, Edwige Battistelli, Angélique de Haze, Stéphanie Bravard, Christelle Tamisier, Françoise Caira, Charles Coutton, Anne‐Laure Barbotin, Angèle Boursier, Laila Lakhal, Claude Beaudoin, David H. Volle   +16 more
wiley   +1 more source

Discovery of 16-Androstenes (Androstenone and Androstenol), Their Synthesis Pathway, and Possible Role in Reproduction of Mouse Deer (Moschiola indica)

Cells, 2022
We discovered odorous 16-androstenes (Androstenone and Androstenol) in endangered mouse deer during a captive breeding program. This study examined the molecular characteristics, their synthesis pathway, and the possible functional role of these compounds in the reproduction of mouse deer.
Vinod Kumar, Shivakumara Manu, Karunakaran Caroline, Anupama Sekhar, Sajwan-Khatri Mamta, Mushkam Sandeep, Wasimuddin ., Balasubramanian Senthilkumaran, Govindhaswamy Umapathy   +8 more
openaire   +2 more sources

Judgements of attractiveness of the opposite sex and nostril differences in self-rated mood: The effects of androstenol

Biological Psychology, 2022
Androstenol has been reported to influence judgements of attractiveness and to affect participants' mood. In the present study, participants were asked to sniff androstenol or a control odour (pure ethanol) unilaterally with the left or right nostril. Subsequently, they rated the attractiveness of photographs of the opposite sex and their own feelings ...
Beaton AA, Jones L, Benton D, Richards G
openaire   +4 more sources

Structure of the Murine Constitutive Androstane Receptor Complexed to Androstenol [PDF]

Molecular Cell, 2004
Shan, Li, Vincent, Jeremy, Brunzelle, Joseph S., Dussault, Isabelle, Lin, Min, Ianculescu, Irina, Sherman, Mark A., Forman, Barry M., Fernandez, Elias J.   +8 more
openaire   +1 more source

Boar pheromone androstenol may affect the ovarian morphology in cycling gilts by humoral pathway.

Folia histochemica et cytobiologica, 2003
Up to 1999 it was accepted that pheromones act exclusively by stimulation of dendritic receptors of olfactory neurons massed in the olfactory epithelium, but in 1999-2000, the presence of local humoral pathway for transfer of boar pheromone androstenol from the nasal cavity to the hypophysis and brain was demonstrated in gilts.
S, Stefańczyk-Krzymowska, B, Wasowska, B, Jana   +2 more
openaire   +1 more source

Does the Androstenol-inhaling effect change through menstrual cycle and by tactile information?

The Proceedings of the Annual Convention of the Japanese Psychological Association, 2012
Yuka SUZUKI, Saho AYABE, Katsuyoshi KAWASAKI, Takamasa KOYAMA   +3 more
openaire   +2 more sources

The estimation of androst-16-en-3α-ol in human urine. Partial synthesis of androstenol and of its β-glucosiduronic acid [PDF]

Biochemical Journal, 1961
B W, Brooksbank, G A, Haslewood
openaire   +2 more sources