Results 121 to 130 of about 87,700 (273)

Whole Blood Transcriptomic Analysis of Sickle Cell Trait

European Journal of Haematology, EarlyView.
ABSTRACT Sickle cell trait (SCT) is the heterozygous carrier state for the HBB missense variant which causes sickle cell disease (SCD). SCT has been associated with increased risk of venous thromboembolism and chronic kidney disease as well as alterations in clinical laboratory parameters. To investigate differential gene expression in SCT, we used RNA
Mari Johnson, Yanwei Cai, Ana Gabriela Vasconcelos, Peter Orchard, Paul L. Auer, Guillaume Lettre, Jia Wen, Nora Franceschini, Charles Kooperberg, Wei Sun, Li Hsu, Laura M. Raffield, Alex P. Reiner   +12 more
wiley   +1 more source

Dynamic regulation of erythropoiesis: A computer model of general applicability [PDF]

A mathematical model for the control of erythropoiesis was developed based on the balance between oxygen supply and demand at a renal oxygen detector which controls erythropoietin release and red cell production.
Leonard, J. I.
core   +1 more source

The PNH French Working Group Experience: Building a Strong Network of Cytometrists

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The PNH working group was created in 2010 to initiate a workshop on testing white blood cells to share international recommendations. Methods Thirty‐five French and Belgian laboratories equipped with 2‐ or 3‐laser cytometers applied three different panels with or without FLAER reagent in 305 samples.
Orianne Wagner‐Ballon, Magali Le Garff‐Tavernier, Rémi Lestestu, Bernard Drenou, Agathe Debliquis, the PNH French Working Group «CytHem‐HPN», Chantal Fossat, Claire Loosen, Bernard Chatelain, Marie Loosveld   +9 more
wiley   +1 more source

Hematologic disorders in systemic lupus erythematosus

Acta Médica del Centro, 2010
A total of 194 cases of patients suffering from systemic lupus erythematosus were reviewed. The hematologic disorders that appeared in the classification criteria were: autoimmune hemolytic anemia (Coombs-positive) in 14 patients (7%), leukopenia in 38 ...
José Francisco Martínez Delgado, Marta Pérez de Alejo Rodríguez, Julio Horaldo López-Silverio Moya   +2 more
doaj  

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Autoimmune hemolytic anemia as presenting manifestation of primary splenic anaplastic large cell lymphoma

The Turkish Journal of Pediatrics, 2006
Autoimmune hemolytic anemia (AIHA) is an unusual complication of malignancy. We diagnosed primary splenic anaplastic large cell lymphoma (ALCL) in a patient. A seven-year-old boy presented with Coombs test-positive hemolytic anemia. After a course
Yavuz Köksal, Umran Calişkan, Canan Uçar, Selim Erekul, Zeynep Ilerisoy Yakut   +4 more
doaj  

Evaluation of the Diagnostic Accuracy of the Quantitative Point‐of‐Care SD Biosensor Standard G6PD Test for Assessment of G6PD Deficiency in Infectious Diseases

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background G6PD deficiency affects about 500 million people worldwide and is prevalent in many malaria‐endemic settings. People with G6PD deficiency are at risk of hemolysis when exposed to certain medications, including 8‐aminoquinoline drugs used to treat Plasmodium vivax malaria.
Flavia Regina Medeiros da Silva, Alexandre Gomes Vizzoni, Daniela Mendes‐de‐Almeida, Joanna Bokel, Raquel de Vasconcellos Carvalhaes de Oliveira, André Machado Siqueira, Yasmine Rangel Vieira, Simone da Costa Cruz Silva   +7 more
wiley   +1 more source

Respiratory Syncytial Virus Vaccine Induced Thrombotic Microangiopathy

Journal of Blood Medicine
Robert Seby,1 Benjamin J McCormick,1 Emily Wolf,2 Justin Kuhlman,2 Nikita Jhawar,1 Sven Peter Oman,1 Adam M Kase,2 Chancey Christenson,3 Marwan Shaikh2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Department of Hematology ...
Seby R, McCormick BJ, Wolf E, Kuhlman J, Jhawar N, Oman SP, Kase AM, Christenson C, Shaikh M   +8 more
doaj  

Spur-Cell Hemolytic Anemia

Annals of Internal Medicine: Clinical Cases
A woman was referred to our hospital for jaundice, subcutaneous bleeding, and anemia. Biopsy findings confirmed liver failure due to alcoholic cirrhosis. A peripheral-blood smear showed red blood cells with irregularly spaced spur-like projections, which
Ayumi Sugiura, Satoru Joshita
doaj   +1 more source