Results 171 to 180 of about 414,209 (326)

Coagulation in the Pathophysiology of Hemolytic Anemias

Hematology, 2007
AbstractCoagulation abnormalities are frequently reported in hemolytic anemias (HA). Several pathophysiologic mechanisms are common to different HA. In this review three different hemolytic disorders will be discussed.In sickle cell disease and in β-thalassemia, a thrombophilic status has been well documented as multifactorial involving hemostatic ...
openaire   +4 more sources

Novel immunotherapies for immune-mediated haemolytic anaemia in dogs and people [PDF]

, 2015
Aerts, Ahmad, Andre, Baek, Baker, Baluna, Barcellini, Bardwell, Barker, Barker, Barker, Bennett, Berentsen, Bielekova, Brode, Brunkow, Buckner, Cancro, Cao, Castela, Corato, Den Otter, Desreumaux, Dieckmann, Dowling, Ellis, Forrester, Gagliani, Garden, Ginzler, Graca, Grant, Grundy, Haagsman, Haase, Hall, Hall, Han, Herzog, Heylmann, Hoffmann, Hori, Hori, Humrich, Impellizeri, Ito, James W Swann, Jubala, Jutel, Keiserman, Kim, Klatzmann, Knueppel, Kojima, Komatsu, Konietschke, Lutz, Mahevas, Mahevas, Marek-Trzonkowska, Mason, McCullough, Meiler, Miller, Miyara, Mouchess, Moyo, Mqadmi, Mueller, Oliver A Garden, Olivry, Packman, Penalver, Pinheiro, Polyak, Putnam, Reff, Reimer, Reynaud, Ring, Rodriguez, Rose, Rosenstein, Rue, Saadoun, Sabatos-Peyton, Sadlack, Sadlack, Sakaguchi, Schabowsky, Sharfe, Singer, Swann, Swann, Thornton, Tischner, Verhagen, Volkmann, Waldron-Lynch, Ward, Whitley, Wildin, Willerford, Wing, Xiao, Xu, Xu, Yadav, Zaja, Zanella, Zhao, Ziekman   +111 more
core   +1 more source

Causes of mortality in koalas autopsied at the University of Melbourne

Australian Veterinary Journal, EarlyView.
Objective To determine the causes of mortality in koalas autopsied at the University of Melbourne based on the retrospective analysis of autopsy reports. Methods The autopsy reports of 239 koalas examined at the University of Melbourne from 1970 to 2023 were reviewed to determine which of the comorbidities present was the primary cause to which death ...
L Wilson, P Whiteley, A Stent, F Stockman, F Elloy, EC Hobbs, VG Astudillo, KVF Jubb, P Loukopoulos   +8 more
wiley   +1 more source

Feline leukaemia virus (FeLV) infection in domestic pet cats in Australia and New Zealand: Guidelines for diagnosis, prevention and management

Australian Veterinary Journal, EarlyView.
Progressive feline leukaemia virus (FeLV) infection dramatically shortens the lives of infected cats, causing acquired immunodeficiency, aplastic anaemia, lymphoma, leukaemia and other myeloproliferative diseases. The potential impact of regressive FeLV infection on the development of disease remains largely unknown, although there is evidence it ...
ME Westman, SJ Coggins, M van Dorsselaer, JM Norris, RA Squires, M Thompson, R Malik   +6 more
wiley   +1 more source

Iron overload in hereditary spherocytosis: Are genetic factors the cause?

British Journal of Haematology, EarlyView.
Summary Non‐transfusional iron overload (IOL) in hereditary spherocytosis (HS) is poorly documented compared with other red blood cell disorders. We studied 13 HS adults with confirmed IOL to identify potential genetic factors. Using a next‐generation sequencing panel of 46 genes related to HS, anaemia and iron metabolism, we found no association ...
Lucie Donaty, Muriel Giansily‐Blaizot, Ivan Bertchansky, Séverine Cunat, Vincent Azoury, Perrine Mahe, Patricia Aguilar Martinez   +6 more
wiley   +1 more source

The anti‐CD47 antibody magrolimab with obinutuzumab and venetoclax in relapsed or refractory indolent B‐cell lymphomas

British Journal of Haematology, EarlyView.
Follicular lymphoma (FL), marginal zone lymphoma (MZL), chronic lymphocytic leukaemia (CLL) and mantle cell lymphoma (MCL) are characterized by a continuous incidence of relapse and increasing resistance to therapy. Novel immunotherapy approaches are needed.
Rahul Lakhotia, Christopher Melani, Stefania Pittaluga, Max J. Gordon, James D. Phelan, Jagan R. Muppidi, Atekelt Tadese, Sarah Evans, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski   +11 more
wiley   +1 more source

Efficacy and safety of HRS‐5965 monotherapy in complement inhibitor–naïve patients with paroxysmal nocturnal haemoglobinuria

British Journal of Haematology, EarlyView.
Summary Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, life‐threatening disorder characterized by complement‐mediated haemolysis, leading to anaemia and thrombosis. HRS‐5965 is a novel, oral, selective complement factor B inhibitor targeting the alternative pathway, potentially reducing both intra‐ and extravascular haemolysis.
Li Zhang, Ziwei Liu, Xin Zhao, Bin Hu, Rong Huang, Chang Shu, Fengkui Zhang, Bing Han   +7 more
wiley   +1 more source

Laboratory assessment of fetomaternal haemorrhage and Rh immune globulin management: Canadian practice and scoping review

British Journal of Haematology, EarlyView.
Fetomaternal haemorrhage (FMH) in RhD‐negative individuals can cause alloimmunization with future antibody‐mediated destruction of fetal red blood cells. Accurate FMH estimation guides Rh immune globulin dosing. The rosette test, the most used qualitative method, may yield false negatives with fetal RhD variants or false positives with maternal ...
Omar I. Hajjaj, Jeannie Callum, Nadine Shehata, Ashley Farrell, Gwen Clarke, Lani Lieberman   +5 more
wiley   +1 more source

Allogeneic transplantation after failure of chimeric antigen receptor‐T cells and exposure to bispecific antibodies: Feasibility, safety and survival outcomes

British Journal of Haematology, EarlyView.
Summary Clinical outcome after chimeric antigen receptor (CAR)‐T‐cell failure in large B‐cell lymphoma (LBCL) is dismal. Allogeneic stem cell transplantation (alloSCT) represents a potentially curative salvage for relapsed/refractory LBCL, although concerns remain regarding its feasibility and safety in patients exposed to CAR‐T and bispecific ...
Angelica Barone, Chiara De Philippis, Federico Stella, Anna Dodero, Barbara Sarina, Martina Pennisi, Armando Santoro, Carmelo Carlo‐Stella, Anna Guidetti, Stefania Bramanti, Paolo Corradini   +10 more
wiley   +1 more source

Systematic Review of Prognostic Factors for Mortality in Dogs with Immune-mediated Hemolytic Anemia [PDF]

, 2015
Altman, Balch, Burgess, Christopher, Duval, Hayden, Hayden, Hayes, Holahan, Hosmer, Ishihara, King, Kjelgaard-Hansen, Klag, McAlees, Moher, Moons, Peduzzi, Piek, Piek, Piek, Piek, Reimer, Riley, Royston, Steyerberg, Swann, Swann, Viera, Weinkle, Whelan   +30 more
core   +1 more source