Results 221 to 230 of about 60,975 (302)

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

American Journal of Hematology, Volume 101, Issue 7, Page 1706-1716, July 2026.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger, Nicolas Hebert, Laura Bencheikh, Vincent Malcor Deydier de Pierrefeu, Anne‐Laure Pham Hung d’Alexandry d’Orengiani, Sandia Adypagavane, Meghan Perkins, Laura Matabishi‐Bibi, France Pirenne, Claire Berquet, Stephane Moutereau, Serge Pissard, Frédéric Galactéros, Michael C. Marden, Pablo Bartolucci   +14 more
wiley   +1 more source

A single-center study: three years of experience with whole-exome sequencing in diagnosing pediatric hematological disorders. [PDF]

Ital J Pediatr
Salah S, Mobarak A, Alshanbari SN, Bukhari AA, Alsobhi F, Farahat SAA, Masmali HM.   +6 more
europepmc   +1 more source

Trends in Corticosteroid Use and Excess in Patients With Inflammatory Bowel Disease in the United States, Sweden, and Denmark

JCC Plus, Volume 1, Issue 4, July 2026.
ABSTRACT Background and Aims Studies show that corticosteroid use in inflammatory bowel disease (IBD) exceeds guideline recommendations. To better understand patterns of corticosteroid use and identify factors associated with excess exposure, we examined long‐term trends in corticosteroid prescribing practices in large IBD populations across 3 ...
Tim Raine, Gil Y. Melmed, J. Casey Chapman, Bobby Lo, Jonas Söderling, Laura E. Targownik, Nidhi Shukla, Si Xuan, Elena Marced Barrachina, Dolly Sharma, Johan Burisch, Ola Olén   +11 more
wiley   +1 more source

Concurrent Hemolytic Anemia and Methemoglobinemia Revealing Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in an Infant Following Peanut Ingestion. [PDF]

Cureus
Ben Mechlia N, Redouane HA, Al-Tamo MO, Hamod L, Mohamed R.   +4 more
europepmc   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri, Andrea Bordugo, Birute Burnyte, Alessandro Costetti, Maria‐Luz Couce, Luisa Diogo, Francois Feillet, D. Sean Froese, Benedetta Greco, Jean‐Louis Gueant, Luciana Hannibal, Friederike Hörster, Viktor Kožich, Giancarlo La Marca, Irini Manoli, Fanny Mochel, Lorenzo Orazi, Belén Pérez, Manuel Schiff, Bernd C. Schwahn, Ida Schwartz, Karolina M. Stepien, Jolanta Sykut‐Cegielska, Trine Tangeraas, Rolf H. Zetterström, Carlo Dionisi‐Vici, Martina Huemer   +26 more
wiley   +1 more source

Delayed-Onset Autoimmune Hemolytic Anemia in Advanced HIV With Cerebral Toxoplasmosis. [PDF]

Cureus
Alahmadi MF, Aldosary O, Bugnah A, Alyami H.   +3 more
europepmc   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

Journal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva, Yann Nadjar, Manuel Schiff, Christine Vianey‐Saban, Alain Fouilhoux, Jean‐François Benoist   +5 more
wiley   +1 more source

Diagnostic Utility of Next-Generation Sequencing for Unconjugated Hyperbilirubinemia in Children. [PDF]

Pediatr Gastroenterol Hepatol Nutr
Kim HJ.
europepmc   +1 more source

Severe maternal morbidity according to sickle cell disease genotype

Pregnancy, Volume 2, Issue 4, July 2026.
Abstract Background Sickle cell disease (SCD) is a genetic hemoglobinopathy that disproportionately affects individuals of African descent and is associated with elevated risks of maternal complications. However, the contribution of specific SCD genotypes to severe maternal morbidity (SMM) and postpartum readmission remains poorly characterized at the ...
Tetsuya Kawakita, Natsume Furukawa, Sora A. Jones, Salimah Navaz Gangji   +3 more
wiley   +1 more source

It's bean too long: Interventions to reintroduce legumes to the UK palate and plate

Annals of Applied Biology, Volume 189, Issue 1, July 2026.
Increased legume consumption can offer considerable health and sustainability benefits. Legume intake in the UK is low, and a number of barriers to intake have been identified. Adopting the Nuffield Council on Bioethics Intervention Ladder, we identify and review an array of interventions—with increasing levels of intervening—that could support ...
Neil Bernard Boyle, Beth Armstrong, Nicola J. Buckland, Laura Lane, Samantha J. Caton, Christian Reynolds, Christina Vogel, Louise Dye   +7 more
wiley   +1 more source