Results 31 to 40 of about 10,017 (230)

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Prevalence of anemia in schools of the metropolitan region of Curitiba, Brazil

Hematology, Transfusion and Cell Therapy, 2018
Background: Anemia during childhood is one of the biggest public health problems worldwide, including Brazil. Insufficient or abnormal production of hemoglobin, loss of iron and excessive destruction of red blood cells are the most common causes of ...
Juliana Spezia, Laísa Ferreira da Silva Carvalho, Marcelo Ferrari de Almeida Camargo-Filho, Aline Emmer Furman, Shirley Ramos da Rosa Utiyama, Railson Henneberg   +5 more
doaj   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

British Journal of Haematology, EarlyView.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed, Rattanaporn Praneetponkang, Potchaman Sittipaisankul, Chayada Thiengtavor, Suwathida Chumpuchanaphai, Kittiphong Paiboonsukwong, Suthat Fucharoen, Kovit Pattanapanyasat, Jim Vadolas, Duncan R. Smith, Saovaros Svasti, Pornthip Chaichompoo   +11 more
wiley   +1 more source

Iron deficiencies: focus on teenage girls [PDF]

РМЖ. Мать и дитя, 2019
T.M. Vasil’eva1,2, I.N. Zakharova1, A.L. Zaplatnikov1,3, N.G. Sugyan1,2, E.V. Shirdanina2, E.A. Doroshina1, L.S. Serikova1, I.D. Maykova3, O.A. Kuznetsova3, A.S. Vorob’eva3, E.R. Radchenko3, L.V. Goncharova3, N.V. Gavelya3 1Russian Medical
T.M. Vasil’eva, I.N. Zakharova, A.L. Zaplatnikov, N.G. Sugyan, E.V. Shirdanina, E.A. Doroshina, L.S. Serikova, I.D. Maikova, Kuznetsova O.A., A.S. Vorob’eva, Radchenko E.R., L.V. Goncharova, Gavel N.V.   +12 more
doaj  

Hemoglobin A2 Cut off Values in Egyptian Cohort as a marker of β -Thalassemia carriers. [PDF]

Journal of Bioscience and Applied Research, 2015
Beta thalassemias (β-thalassemias) are a group of inherited blood disorders caused by reduced or absent synthesis of beta chains of hemoglobin resulting in variable phenotypes ranging from severe anemia to clinically asymptomatic individuals.
Noura Kablan, Manal El Hamshary, Ghada Nasr, Mohamed Hamza, Tarif Salam, Alaa Hemeida   +5 more
doaj   +1 more source

The iron content of gastric juice: in relation to the cause of idiopathic hypochromic anemia

, 1967
Non-hemin iron content in gastric juice was examined in 46 patients with various blood diseases, especially idiopathic hypochromic anemia and in 26 healthy controls. 1. The iron content in gastric juice was found to be 290 μg/ dl in healthy controls,
Kimura, Ikuro, Yamana, Masatoshi
core   +1 more source

Double trouble: A case of fraternal twins with iron‐refractory iron‐deficiency anemia

Clinical Case Reports, 2022
Iron‐refractory iron‐deficiency anemia (IRIDA) is a rare autosomal recessive disease that presents in childhood. We report the case of fraternal twins presenting with severe hypochromic microcytic anemia and hypoferritinemia.
Jacques A. J. Malherbe, Catherine H. Cole   +1 more
doaj   +1 more source

Refractory microcytic hypochromic anemia with type I diabetes mellitus and reversible cardiac hemochromatosis in congenital hypotransferrinemia

Pediatric Hematology Oncology Journal
Background: Hypotransferrinemia is a rare cause of anemia presenting in early childhood. The clinical scenario may mimic iron deficiency anemia at onset with no response to multiple courses of hematinics.
Shrikiran Aroor, Suneel C. Mundkur, Sandeep Kumar, Koushik Handattu, Praveen C. Samuel   +4 more
doaj   +1 more source