Results 71 to 80 of about 10,017 (230)
ABSTRACT Background and Aims The polymerization of deoxygenated hemoglobin S, resulting from a genetic mutation in sickle cell disease (SCD), leads to damage in multiple organs, including renal, cardiopulmonary, and cerebrovascular systems. The liver is also commonly affected, resulting in “sickle cell liver disease,” which may lead to progressive ...
Josué Louokdom Simo +6 more
wiley +1 more source
Background: Hemoglobinopathies are the most common inherited red cell disorders worldwide. Identification of these disorders is immensely important epidemiologically and for improved management protocols.
Ravi Shankar Sarkar +2 more
core +1 more source
Anemia among Children Aged 1 month -12 Years at Al-Wahda Hospital, Derna-Libya
Anemia is one of the main public health issues among children in the world. The causes of anemia are multifactorial, but iron deficiency is the most common one. There are direct proportions between iron and body mass.
Aziza M. Alsheekh, Amal S. Alhassadi
doaj +1 more source
ABSTRACT Background and Aim Endogenous erythropoietin (EPO) deficiency has been associated with anemia in patients with type 2 diabetes mellitus (T2DM) and renal injury. The purpose of this study was to characterize EPO levels and anemia in Vietnamese patients with T2DM and chronic kidney disease (CKD).
Nguyen Ngoc Anh +3 more
wiley +1 more source
Calreticulin Type 26 Mutation in Myelofibrosis: A Rare Variant With Diagnostic Challenges
ABSTRACT Background Myeloproliferative neoplasms (MPNs) are clonal hematologic disorders commonly driven by mutations in JAK2, MPL, or CALR. Because routine CALR assays are largely optimized for the canonical Type 1 and Type 2 exon 9 variants, rare noncanonical mutations may be missed, creating diagnostic challenges.
Teresa Maltese +6 more
wiley +1 more source
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source
The Mindray 6800 Plus analyzer reports red cells (RBC) extended parameters, which represent the subsets of erythrocytes. We aimed to evaluate the reliability of RBC extended parameters in the differential diagnosis of microcytic anemia.
Eloísa Urrechaga
core +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
The differentiation between iron deficiency anemia (IDA) and β-thalassemia trait (βTT) is essential for managing microcytic hypochromic anemia. Indices such as the Mentzer Index (MI) and Red Cell Distribution Width Index (RDWI) serve as cost-effective ...
Rabab H. Elshaikh +9 more
doaj +1 more source
BACKGROUND: Thalassemia trait and other low red cell index (LRCI) diseases commonly have same presentation with microcytic hypochromic anemia. Most of beta thalassemia minor (TM) people are subclinical and without specific investigation may be ...
Safa A Faraj +2 more
doaj +1 more source

