Results 241 to 250 of about 211,029 (346)

Healthy Aging Metabolomic and Proteomic Signatures Across Multiple Physiological Compartments

open access: yesAging Cell, EarlyView.
The association of the aging scores with the clinical covariates suggests increased inflammation, strong predisposition to iron deficiency anemia, decline in muscle mass, and renal and hepatic functions with accelerated aging. ABSTRACT The study of biomarkers in biofluids and tissues expanded our understanding of the biological processes that drive ...
R. Moaddel   +17 more
wiley   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk   +6 more
wiley   +1 more source

Significant kidney disease in pregnancy: Feasibility and outcomes of a national population‐based study using the Australasian Maternity Outcomes Surveillance System

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
Background Current understanding of clinical practice and care for maternal kidney disease in pregnancy in Australia is hampered by limitations in available renal‐specific datasets. Aims To capture the epidemiology, management, and outcomes of women with significant kidney disease in pregnancy and demonstrate feasibility of a national cohort study ...
Shilpanjali Jesudason   +8 more
wiley   +1 more source

Evaluation of renal function with neutrophil gelatinase-associated lipocalin in patients with ıron deficiency anemia. [PDF]

open access: yesSci Rep
Çetintulum Aydın B   +6 more
europepmc   +1 more source

Position statement on the management of pregnancy in sickle cell disease

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
Sickle cell disease (SCD) is a hereditary haemoglobinopathy which causes multi‐organ dysfunction. Pregnancies in SCD are high risk with significant maternal and fetal morbidity and mortality, including vaso‐occlusive crises, thrombosis, anaemia, placental insufficiency, fetal growth restriction, preterm birth and medication effects. High level evidence
Mimi Yue   +5 more
wiley   +1 more source

Provision of peri‐operative patient blood management strategies in the UK: a national survey of practice

open access: yesAnaesthesia, EarlyView.
Summary Introduction In UK hospitals, it is unclear how organisational structures are arranged to support effective implementation of peri‐operative blood management practice strategies. The aim of this study was to conduct a national survey of organisations to describe local practices of peri‐operative patient blood management and infrastructure ...
Samantha R. Warnakulasuriya   +155 more
wiley   +1 more source

The use of iron after surgery: a systematic review and meta‐analysis

open access: yesAnaesthesia, EarlyView.
Summary Introduction Anaemia in patients having surgery is associated with worse postoperative outcomes. Management with intravenous iron is an attractive therapeutic option, however, pre‐operative intravenous iron administration is challenging. Evidence from interventional trials suggests that the greatest benefit is after hospital discharge.
Jayne Lim   +3 more
wiley   +1 more source

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