How to use luspatercept and erythropoiesis‐stimulating agents in low‐risk myelodysplastic syndrome
Summary Anaemia is the most common cytopenia in myelodysplastic syndrome (MDS), significantly impacting quality of life and morbidity. Erythropoiesis‐stimulating agents (ESAs) are the first‐line treatment for anaemia in lower risk (LR)‐MDS. The European Medicines Agency (EMA) approved epoetin alpha for LR‐MDS‐related anaemia in 2017, based on evidence ...
Valeria Santini, Angela Consagra
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Ferritin outperforms other biomarkers in predicting bone marrow iron stores in patients with hematologic disorders. [PDF]
Lahtiharju T+4 more
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The Causal Effect of Iron Traits on Risk of Hypertrophic Scarring: A Two-Sample Mendelian Randomization Study. [PDF]
Bian D, Gong H, Shi W.
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Maternal-Infant Iron Deficiency and Neurologic Sequelae. [PDF]
Felt BT, Tran PV.
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GGCT Inhibits Ferroptosis in PTC Cells by Upregulating p53 Through RPS15A
Our results showed that γ‐glutamine cyclotransferase (GGCT) knockdown in PTC cells inhibited GSH synthesis, promoted the malignant accumulation of malondialdehyde (MDA) and reactive oxygen species (ROS), and finally promoted cell ferroptosis. In vivo experiments showed that Pro‐GA, a specific inhibitor of GGCT, inhibited the subcutaneous tumorigenesis ...
Hui‐min Zhang+9 more
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Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy. [PDF]
Fatima N+13 more
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ABSTRACT Introduction Saliva hormone measurement is increasingly being applied in everyday clinical practice. In relation to salivary cortisone measurement, there is a particular advantage, with minimal chance of cross‐reaction with prescribed glucocorticoids and greater convenience.
Mathilde Mordaunt+10 more
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Lack of association between the TMPRSS6 gene polymorphism (rs855791) and anemia: a comprehensive meta-analysis. [PDF]
Muruganantham JK, Veerabathiran R.
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Abstract Aims HbA1c testing in African populations may be limited due to high prevalence of hemoglobinopathies, anaemia, malaria and renal impairment. We aimed to assess the performance of glycated albumin (GA) and fructosamine in comparison to HbA1c for determining glycaemic control in Africans living with type 2 diabetes.
Anxious J. Niwaha+6 more
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Prevalence and sociodemographic determinants of anemia among ever-married women of reproductive age in Jordan: insights from the 2023 Jordan population and family health survey. [PDF]
Ibrahim AAA+3 more
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