Results 281 to 290 of about 211,029 (346)

How to use luspatercept and erythropoiesis‐stimulating agents in low‐risk myelodysplastic syndrome

open access: yesBritish Journal of Haematology, EarlyView.
Summary Anaemia is the most common cytopenia in myelodysplastic syndrome (MDS), significantly impacting quality of life and morbidity. Erythropoiesis‐stimulating agents (ESAs) are the first‐line treatment for anaemia in lower risk (LR)‐MDS. The European Medicines Agency (EMA) approved epoetin alpha for LR‐MDS‐related anaemia in 2017, based on evidence ...
Valeria Santini, Angela Consagra
wiley   +1 more source

GGCT Inhibits Ferroptosis in PTC Cells by Upregulating p53 Through RPS15A

open access: yesCancer Science, EarlyView.
Our results showed that γ‐glutamine cyclotransferase (GGCT) knockdown in PTC cells inhibited GSH synthesis, promoted the malignant accumulation of malondialdehyde (MDA) and reactive oxygen species (ROS), and finally promoted cell ferroptosis. In vivo experiments showed that Pro‐GA, a specific inhibitor of GGCT, inhibited the subcutaneous tumorigenesis ...
Hui‐min Zhang   +9 more
wiley   +1 more source

Micro-nutrient sufficiency in mothers and babies: management of deficiencies while avoiding overload during pregnancy. [PDF]

open access: yesFront Nutr
Fatima N   +13 more
europepmc   +1 more source

Morning Salivary Cortisone Versus Serum Cortisol in the Overnight Dexamethasone Suppression Test (ODNST): Evaluation in a Clinical Setting

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Saliva hormone measurement is increasingly being applied in everyday clinical practice. In relation to salivary cortisone measurement, there is a particular advantage, with minimal chance of cross‐reaction with prescribed glucocorticoids and greater convenience.
Mathilde Mordaunt   +10 more
wiley   +1 more source

Glycated albumin and fructosamine do not improve accuracy of glycaemic control assessment in patients with conditions reported to affect HbA1c reliability

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims HbA1c testing in African populations may be limited due to high prevalence of hemoglobinopathies, anaemia, malaria and renal impairment. We aimed to assess the performance of glycated albumin (GA) and fructosamine in comparison to HbA1c for determining glycaemic control in Africans living with type 2 diabetes.
Anxious J. Niwaha   +6 more
wiley   +1 more source

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