Results 41 to 50 of about 237,257 (291)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Ability of serum ferritin to diagnose iron deficiency anemia in an elderly cohort

Revista Brasileira de Hematologia e Hemoterapia
Background Diagnosis and treatment of iron deficiency anemia in older subjects improves their quality of life. Serum ferritin as a marker of iron stores is an acute phase protein.
Mansour Babaei, Sajedeh Shafiei, Ali Bijani, Behzad Heidari, Seyed Reza Hosseyni, Mohsen Vakili Sadeghi   +5 more
doaj   +1 more source

Iron Deficiency Anemia in Children Residing in High and Low-Income Countries: Risk Factors, Prevention, Diagnosis and Therapy

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Iron deficiency and iron-deficiency anemia (IDA) affects approximately two billion people worldwide, and most of them reside in low- and middle-income countries.
E. Mantadakis
semanticscholar   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Red cell distribution width’s role in differentiating iron deficiency anemia from other hypochromic microcytic anemias

Zanco Journal of Medical Sciences, 2021
Background and objective: The red cell distribution width is suggested to be a more sensitive indicator for microcytic hypochromic anemia. Therefore, this study aimed to determine the role of red cell distribution width in the diagnosis of iron ...
Shno Ibrahim Hussein, Abbas Abdulkadir Rabaty   +1 more
doaj   +1 more source

Low Dose Daily Iron Supplementation Improves Iron Status and Appetite but not Anemia, Whereas Quarterly Anthelminthic Treatment Improves Growth, Appetite and Anemia in Zanzibari Preschool Children. [PDF]

, 2004
Iron deficiency and helminth infections are two common conditions of children in developing countries. The consequences of helminth infection in young children are not well described, and the efficacy of low dose iron supplementation is not well ...
Adam, Albonico, Albonico, Antonio Montresor, Brown, Caulfield, Crompton, Davis, de Andraca, Dickson, Diggle, Donnen, Freij, Greenberg, Gupta, Gupta, Hababu M. Chway, Idjradinata, James M. Tielsch, Jape Khatib Jape, Jelkmann, Kloetzel, Lackritz, Langhans, Levin, Lorenzo Savioli, Lozoff, Marco Albonico, Menendez, Montresor, National Research Council, Nelson, Pelletier, Pinero, Plata-Salaman, Rebecca J. Stoltzfus, Reeds, Rosenberg, Rousham, Savioli, Schultz, Smith, Solomons, Stoltzfus, Stoltzfus, Stoltzfus, Stoltzfus, Thein-Hlaing, Trape, Verhoef, Warren, Willett, World Health Organization, World Health Organization Expert Committee   +53 more
core   +1 more source

A Review of Clinical Guidelines on the Management of Iron Deficiency and Iron-Deficiency Anemia in Women with Heavy Menstrual Bleeding

Advances in Therapy, 2020
Introduction Up to one-third of women of reproductive age experience heavy menstrual bleeding (HMB). HMB can give rise to iron deficiency (ID) and, in severe cases, iron-deficiency anemia (IDA). Aim To review current guidelines for the management of HMB,
D. Mansour, A. Hofmann, K. Gemzell‐Danielsson   +2 more
semanticscholar   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

The Clinical and Biological Manifestations in Women with Iron Deficiency Without Anemia Compared to Iron Deficiency Anemia in a General Internal Medicine Setting: A Retrospective Cohort Study

International Journal of General Medicine, 2022
Takanobu Hirosawa, Arisa Hayashi, Yukinori Harada, Taro Shimizu Department of Diagnostic and Generalist Medicine, Dokkyo Medical University, Tochigi, JapanCorrespondence: Taro Shimizu, Department of Diagnostic and Generalist Medicine, Dokkyo Medical ...
Hirosawa T, Hayashi A, Harada Y, Shimizu T   +3 more
doaj  

Sol–gel synthesis and thermal behavior of bioactive ferrous citrate–silica hybrid materials [PDF]

, 2018
Imbalance of the iron level in the body causes several diseases. In particular, the low level of iron, during pregnancy, is responsible for the iron deficiency anemia, and even of neurodegenerative diseases.
Catauro, M., Naviglio, D., Risoluti, R., Vecchio, Ciprioti   +3 more
core   +1 more source