Results 41 to 50 of about 68,197 (263)

Systemic Bevacizumab for Severe Bleeding From Acquired Gastrointestinal Vascular Malformations

American Journal of Hematology, EarlyView.
Targeted antiangiogenic therapy with systemic bevacizumab for bleeding from acquired GI VMs was found to be safe and effective for chronic and severe bleeding from acquired vascular malformations due to idiopathic angiodysplasia, chronic liver disease, and deficiencies of von Willebrand factor, in a patient population comprised mostly of heavily ...
Nardeen E. Ayad, Jacob R. Anderson, Bimalangshu Dey, Rebecca Karp Leaf, Andrew B. Song, Hanny Al‐Samkari   +5 more
wiley   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Gastrointestinal malignancy in iron deficiency without anemia: a retrospective study from Jordan

Scientific Reports
Guidelines clearly recommend endoscopic investigation for iron deficiency anemia but are ambiguous for iron deficiency without anemia. We aimed to compare gastrointestinal malignancy rates between patients with iron deficiency without anemia and iron ...
Sara Haj Ali, Awni Abu Sneineh, Bashar Quteishat, Raghad Nabhan, Ala’a Mohammad, Rasha Ali, Jana Alsokhon, Said Lahham, Neebal Mosleh, Mera Jaber, Rand Khawaldeh, Safa Alhusaini   +11 more
doaj   +1 more source

Pathways for the regulation of hepcidin expression in anemia of chronic disease and iron deficiency anemia in vivo

Haematologica, 2011
Background Increased levels of hepcidin, the master regulator of iron homeostasis, contribute to the diversion of iron underlying the anemia of chronic disease.
Igor Theurl, Andrea Schroll, Manfred Nairz, Markus Seifert, Milan Theurl, Thomas Sonnweber, Hasan Kulaksiz, Guenter Weiss   +7 more
doaj   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

The prevalence of Iron Deficiency and Its Anemia in 1-5 Years Old Children and Their Mothers in Birjand City

Journal of Fasa University of Medical Sciences, 2014
Background &Objective: Micronutrient deficiencies are the most common nutritional disorders in the world in which iron deficiency is the most important one.
Azita Fesharakinia
doaj  

Hemopexin Purification From Human Cohn Fraction IV Paste and Its Biophysical Characterization and Functional Evaluation in Sickle Cell Disease Mice

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hemopexin (Hpx) is an acute phase plasma protein that is responsible for sequestration and removal of cell‐free heme with very high affinity (Kd < 1 pM). Hpx expression in liver cells is induced following an inflammatory event such as severe hemolysis. Therefore, plasma Hpx has potential clinical relevance due to its' ability to bind free heme,
Shuwei Lu, Saini Setua, Mohd A. Khan, Aaradhya Bansal, Quintin O'Boyle, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +8 more
wiley   +1 more source

The evaluation of iron deficiency and anemia in male blood donors with other related factors

Asian Journal of Transfusion Science, 2010
Aims and Background: Iron deficiency is one of the most common nutritional disorders worldwide and blood donation may cause iron depletion. Limited studies with large sample size have been done on male donors.
Yousefinejad Vahid, Darvishi Nazila, Arabzadeh Masoumeh, Soori Masoumeh, Magsudlu Mahtab, Shafiayan Madjid   +5 more
doaj  

Evaluation of oxidative status in iron deficiency anemia through total antioxidant capacity measured using an automated method

Turkish Journal of Hematology, 2011
OBJECTIVE: Oxidative stress, an increase in oxidants and/or a decrease in antioxidant capacity, is one of the potential biochemical mechanisms involved in the pathogenesis of iron deficiency anemia.
Mehmet Aslan, Mehmet Horoz, Hakim Çelik
doaj   +3 more sources

Immunoglobulin and Iron Deficiency Anemia [PDF]

Indian Journal of Hematology and Blood Transfusion, 2011
I read the recent publication on immunoglobulin and iron deficiency anemia with a great interest [1]. Sadeghian et al. [1] concluded that “serum immunoglobulin levels did not change in iron deficiency anemia.” This report is concordant with some previous reports such as the reports by Bagchi et al. [2].
openaire   +2 more sources