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TREATMENT OF MACROCYTIC ANEMIAS
Archives of Internal Medicine, 1955ANEMIAS characterized by large erythrocytes (MCV > 95) are usually caused by lack of one of the erythrocyte maturation factors, vitamin B12or folinic acid. Under these circumstances the young erythrocytes in the bone marrow are megaloblastic and maturation of myeloid elements and megakaryocytes is bizarre.
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Normocytic and macrocytic anemias
Postgraduate Medicine, 1991Differential diagnosis of normocytic and macrocytic anemias is guided by the patient history, physical examination results, reticulocyte count, and specific red blood cell abnormalities identified on the peripheral smear. In some cases this information is sufficient for diagnosis.
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FP essentials, 2023
Macrocytic anemia is divided into megaloblastic and nonmegaloblastic causes, with the former being more common. Megaloblastic anemia results from impaired DNA synthesis, leading to release of megaloblasts, which are large nucleated red blood cell precursors with chromatin that is not condensed.
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Macrocytic anemia is divided into megaloblastic and nonmegaloblastic causes, with the former being more common. Megaloblastic anemia results from impaired DNA synthesis, leading to release of megaloblasts, which are large nucleated red blood cell precursors with chromatin that is not condensed.
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Clinching the diagnosis: macrocytic anemia
Pathology, 1988Macrocytosis is a common laboratory finding. Whether this change requires further attention is dictated by clinical circumstances and concomitant cytopenias or aberrant erythrocyte and leukocyte morphology. The utility of these changes for dictating further investigation and the appropriate "modus operandi" in diagnostic strategies for the adult and ...
M B, Van der Weyden, L, Campbell
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Investigation of macrocytic anemia
Postgraduate Medicine, 1979This article on microcytic anemia is the first of several on laboratory investigation of anemia. Microcytic anemia, characterized by a mean corpuscular volume of less than 80 cu mu, is usually due to iron deficiency or chronic disease but may signify thalassemia minor. Exact identification of the cause is important, since inappropriate iron therapy may
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La Revue du praticien, 1989
Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms).
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Macrocytic and/or megaloblastic anaemias of infants and children are more often due to a defective bone marrow production than to haemolysis. They are mostly related to folate and/or cobalamin deficiency or to a disturbance in the metabolism of one of these vitamins (enzyme deficiencies or defect of synthesis of their active forms).
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American family physician, 1996
In approximately 2 to 4 percent of patients, laboratory evidence of macrocytosis is found. Macrocytic anemias are classified as those resulting from disorders of DNA synthesis of erythrocyte precursors in bone marrow (megaloblastic anemias) or those caused primarily by alcoholism, liver disease and hypothyroidism (nonmegaloblastic anemias).
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In approximately 2 to 4 percent of patients, laboratory evidence of macrocytosis is found. Macrocytic anemias are classified as those resulting from disorders of DNA synthesis of erythrocyte precursors in bone marrow (megaloblastic anemias) or those caused primarily by alcoholism, liver disease and hypothyroidism (nonmegaloblastic anemias).
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MACROCYTIC ANEMIA OF PREGNANCY
Journal of the American Medical Association, 1944To the Editor:— The rare macrocytic anemia of pregnancy is a serious and incompletely understood disease. Some writers have considered it a form of pernicious anemia, but most observers have been impressed particularly by its resemblance to the hemolytic anemias.
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Amisulpride-Induced Macrocytic Anemia
The Journal of Neuropsychiatry and Clinical Neurosciences, 2013Sujit, Sarkhel +2 more
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