Results 201 to 210 of about 296,118 (259)
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Evaluation of Macrocytic Anemias
Seminars in Hematology, 2015Macrocytic anemia, defined as a mean cell volume (MCV) ≥100 fL in adults, has a narrow differential diagnosis that requires evaluation of the peripheral blood smear as well as additional laboratory testing taken in conjunction with clinical information that includes patient history and physical examination findings.
Ralph Green, Denis M. Dwyre
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ZRSR2 mutation in a child with refractory macrocytic anemia and Down Syndrome
Pediatric Hematology & Oncology, 2019Here we report a case of refractory macrocytic anemia with a spliceosomal point mutation involving the ZRSR2 gene in a child with Down syndrome (DS). Such mutations have been shown to cause refractory macrocytic anemia and myelodysplastic syndrome (MDS ...
M. Srinath +8 more
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Zhongguo shi yan xue ye xue za zhi, 2019
OBJECTIVE To study the etiology of macrocytic anemia in elderly patients and to evaluate the diagnostic significance of laborotory tests. METHODS 133 elderly macrocytic anemia patients, whose age>60 years old, hemoglobin100 fL, and bone marrow cell ...
Dong Zhou +4 more
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OBJECTIVE To study the etiology of macrocytic anemia in elderly patients and to evaluate the diagnostic significance of laborotory tests. METHODS 133 elderly macrocytic anemia patients, whose age>60 years old, hemoglobin100 fL, and bone marrow cell ...
Dong Zhou +4 more
semanticscholar +1 more source
Pediatric Blood & Cancer, 2022
Diamond–Blackfan anemia (DBA) is an inherited bone marrow failure syndrome, associated with mutations in ribosomal protein (RP) genes. Growing data on mutations in non‐RP genes in patients with DBA‐like phenotype became available over recent years.
D. Fedorova +6 more
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Diamond–Blackfan anemia (DBA) is an inherited bone marrow failure syndrome, associated with mutations in ribosomal protein (RP) genes. Growing data on mutations in non‐RP genes in patients with DBA‐like phenotype became available over recent years.
D. Fedorova +6 more
semanticscholar +1 more source
Thrombotic Microangiopathy-Like Hemolysis in Vitamin B12 Deficiency-Related Macrocytic Anemia.
Clinical Laboratory, 2018BACKGROUND Hemolytic features in patients with pernicious anemia have not been emphasized. METHODS Seven Japanese patients at 60 - 88 years of age with vitamin B12 deficiency-related hemolytic anemia were assessed. RESULTS Serum vitamin B12 levels in
M. Yamanishi +4 more
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Current Opinion in Hematology
Purpose of review Over the last century, the diseases associated with macrocytic anemia have been changing with more patients currently having hematological diseases including malignancies and myelodysplastic syndrome. The intracellular mechanisms underlying the development of anemia with macrocytosis can help in understanding ...
Mark J, Koury, Daniel J, Hausrath
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Purpose of review Over the last century, the diseases associated with macrocytic anemia have been changing with more patients currently having hematological diseases including malignancies and myelodysplastic syndrome. The intracellular mechanisms underlying the development of anemia with macrocytosis can help in understanding ...
Mark J, Koury, Daniel J, Hausrath
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Macrocytic anemia of pregnancy and anemia of the newborn
American Journal of Obstetrics and Gynecology, 1939Abstract The relationship of macrocytic anemia of pregnancy with a severe anemia of the newborn is herein reported, with a discussion of the etiologic factors involved. We believe that the anemia of both the mother and the infant is due to a dietary deficiency.
Joseph A. Ritter, Walter J. Crocker
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Postgraduate Medicine, 1977
Macrocytic anemias are not uncommon in clinical practice, and precise etiologic diagnosis is mandatory for proper management. Measurement of serum levels of vitamin B12 and folic acid may obviate the need for extensive diagnostic studies.
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Macrocytic anemias are not uncommon in clinical practice, and precise etiologic diagnosis is mandatory for proper management. Measurement of serum levels of vitamin B12 and folic acid may obviate the need for extensive diagnostic studies.
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Clinching the diagnosis: macrocytic anemia
Pathology, 1988Macrocytosis is a common laboratory finding. Whether this change requires further attention is dictated by clinical circumstances and concomitant cytopenias or aberrant erythrocyte and leukocyte morphology. The utility of these changes for dictating further investigation and the appropriate "modus operandi" in diagnostic strategies for the adult and ...
Lynda Campbell, Martin B. Van Der Weyden
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TREATMENT OF MACROCYTIC ANEMIAS
Archives of Internal Medicine, 1955ANEMIAS characterized by large erythrocytes (MCV > 95) are usually caused by lack of one of the erythrocyte maturation factors, vitamin B12or folinic acid. Under these circumstances the young erythrocytes in the bone marrow are megaloblastic and maturation of myeloid elements and megakaryocytes is bizarre.
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