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Analysis of Mean Corpuscular Volume and Red Cell Distribution Width in Patients with Aplastic Anemia
Hemoglobin, 2023To explore the characteristics of hemogram in patients with aplastic anemia (AA), especially mean corpuscular volume (MCV) and red cell distribution width (RDW).
Lingling Liu+9 more
semanticscholar +1 more source
Laboratory Medicine, 1990
Megaloblastic anemias result from processes that disrupt DNA synthesis. The condition is usually acquired, with medications, cobalamin, or folate deficiency being common precipitating factors. Many patients with cobalamin or folate deficiency will present with hematologic abnormalities, such as anemia or pancytopenia, along with macroovalocytes and ...
John A. Glaspy, Steven M. Scates
openaire +2 more sources
Megaloblastic anemias result from processes that disrupt DNA synthesis. The condition is usually acquired, with medications, cobalamin, or folate deficiency being common precipitating factors. Many patients with cobalamin or folate deficiency will present with hematologic abnormalities, such as anemia or pancytopenia, along with macroovalocytes and ...
John A. Glaspy, Steven M. Scates
openaire +2 more sources
A Case of Pernicious Anemia Presenting With Severe Hemolysis
Cureus, 2023Vitamin B12 deficiency is a well-known and overall common disease. While the etiology of vitamin B12 deficiency varies from post-surgical changes to inadequate dietary consumption, pernicious anemia should be considered as it is a common cause ...
Kaitlyn N Romero+4 more
semanticscholar +1 more source
Evaluation of Macrocytic Anemias
Seminars in Hematology, 2015Macrocytic anemia, defined as a mean cell volume (MCV) ≥100 fL in adults, has a narrow differential diagnosis that requires evaluation of the peripheral blood smear as well as additional laboratory testing taken in conjunction with clinical information that includes patient history and physical examination findings.
Ralph Green, Denis M. Dwyre
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Zhongguo shi yan xue ye xue za zhi, 2019
OBJECTIVE To study the etiology of macrocytic anemia in elderly patients and to evaluate the diagnostic significance of laborotory tests. METHODS 133 elderly macrocytic anemia patients, whose age>60 years old, hemoglobin100 fL, and bone marrow cell ...
Dong Zhou+4 more
semanticscholar +1 more source
OBJECTIVE To study the etiology of macrocytic anemia in elderly patients and to evaluate the diagnostic significance of laborotory tests. METHODS 133 elderly macrocytic anemia patients, whose age>60 years old, hemoglobin100 fL, and bone marrow cell ...
Dong Zhou+4 more
semanticscholar +1 more source
ZRSR2 mutation in a child with refractory macrocytic anemia and Down Syndrome
Pediatric Hematology & Oncology, 2019Here we report a case of refractory macrocytic anemia with a spliceosomal point mutation involving the ZRSR2 gene in a child with Down syndrome (DS). Such mutations have been shown to cause refractory macrocytic anemia and myelodysplastic syndrome (MDS ...
M. Srinath+8 more
semanticscholar +1 more source
Pediatric Blood & Cancer, 2022
Diamond–Blackfan anemia (DBA) is an inherited bone marrow failure syndrome, associated with mutations in ribosomal protein (RP) genes. Growing data on mutations in non‐RP genes in patients with DBA‐like phenotype became available over recent years.
D. Fedorova+6 more
semanticscholar +1 more source
Diamond–Blackfan anemia (DBA) is an inherited bone marrow failure syndrome, associated with mutations in ribosomal protein (RP) genes. Growing data on mutations in non‐RP genes in patients with DBA‐like phenotype became available over recent years.
D. Fedorova+6 more
semanticscholar +1 more source
Thrombotic Microangiopathy-Like Hemolysis in Vitamin B12 Deficiency-Related Macrocytic Anemia.
Clinical Laboratory, 2018BACKGROUND Hemolytic features in patients with pernicious anemia have not been emphasized. METHODS Seven Japanese patients at 60 - 88 years of age with vitamin B12 deficiency-related hemolytic anemia were assessed. RESULTS Serum vitamin B12 levels in
M. Yamanishi+4 more
semanticscholar +1 more source