Results 61 to 70 of about 9,719 (222)

Olaparib Plus Abiraterone in Asian Patients With Metastatic Castration‐Resistant Prostate Cancer: PROpel Subset Analysis

Cancer Science, Volume 116, Issue 6, Page 1638-1647, June 2025.
In the phase 3 PROpel trial (NCT03732820), first‐line treatment with olaparib plus abiraterone significantly prolonged radiographic progression‐free survival (rPFS) and numerically prolonged overall survival (OS) versus placebo plus abiraterone in patients with metastatic castration‐resistant prostate cancer (mCRPC).
Mototsugu Oya, Jae Young Joung, Ji Youl Lee, Mikio Sugimoto, Young Deuk Choi, Jun Hyuk Hong, Hiroji Uemura, Kazuo Nishimura, Hideyasu Tsumura, Satoru Kawakami, Yukiyoshi Hirayama, Tae Gyun Kwon, Cheol Kwak, Hiroyoshi Suzuki, Tomoko Fujita, Masahiro Nii, David McGuinness, Melanie Dujka, Christian Poehlein, Fred Saad, Noel Clarke   +20 more
wiley   +1 more source

Recognizing missed opportunities to diagnose and treat iron deficiency anemia: A study based on prevalence of anemia among children in a teaching hospital

Journal of Family Medicine and Primary Care, 2019
Background: In developing world, anemia is a significant cause of mortality and morbidity in children under 5 years of age. Iron deficiency anemia (IDA) is a very important causative factor for childhood anemia.
Dipshikha Maiti, Suchi Acharya, Surupa Basu   +2 more
doaj   +1 more source

Anemia [PDF]

, 2009
This issue of eMedRef provides information to clinicians on the pathophysiology, diagnosis, and therapeutics of ...
Brill, John
core   +1 more source

Familial RPL26 Variant Causing Congenital Anomalies Without Hematological Features of Diamond Blackfan Anemia

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT Diamond Blackfan anemia (DBA) is an autosomal dominant disorder with a heterogeneous clinical presentation which may include macrocytic anemia typically presenting in the first year of life, growth retardation, and congenital malformations in 30%–50% of patients.
Lisa M. Karger, Bryn D. Webb, Lisa Edelmann, Jun Liao, Lakshmi Mehta   +4 more
wiley   +1 more source

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations

Cancer Medicine, 2020
Large granular lymphocyte (LGL) leukemia is a rare hematological disorder with expansion of the T‐cell or natural killer (NK) cell lineage. Signal transducer and activator of transcription 3 (STAT3) exhibits somatic activating mutations in 30%‐40% of LGL
Kristine C. Olson, Katharine B. Moosic, Marieke K. Jones, Paige M. K. Larkin, Thomas L. Olson, Mariella F. Toro, Todd E. Fox, David J. Feith, Thomas P. Loughran Jr   +8 more
doaj   +1 more source

Erythropoiesis during recovery from macrocytic anemia: macrocytes, normocytes, and microcytes [PDF]

Blood, 1977
Abstract In seven patients with marked megaloblastic anemia (MCV greater than 110 fl), red cell size distribution curves (erythrograms) demonstrated the size of red cells produced after therapy. In six, the new red cells were normocytic throughout recovery.
openaire   +4 more sources

Real‐world outcomes of vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome at a tertiary referral centre

British Journal of Haematology, EarlyView.
Lucia Lee, Eric J. Zhao, Robert Schmidt, Alym Abdulla, Gayatri Sreenivasan, Kimberley Ambler, Megan Hiltz, Lynda Foltz, Vicki Chan, Alexandra Legge, Maggie Yuen, Lauren Lee, Paul Yenson, Thomas J. Nevill, Luke Y. C. Chen, Ryan J. Stubbins   +15 more
wiley   +1 more source

MetALD: New Perspectives on an Old Overlooked Disease

Liver International, Volume 45, Issue 5, May 2025.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease (ALD) are the major contributors to the liver disease burden globally. The rise in these conditions is linked to obesity, type 2 diabetes, metabolic syndrome and increased alcohol consumption.
Gustavo Ayares, Luis Antonio Diaz, Francisco Idalsoaga, Naim Alkhouri, Mazen Noureddin, Ramon Bataller, Rohit Loomba, Juan Pablo Arab, Marco Arrese   +8 more
wiley   +1 more source

Evaluation of anaemia [PDF]

, 2017
Background: Often, the first test used to diagnose anemia is a complete blood count (CBC). It determines the number, size, volume, and hemoglobin content of red blood cells. Peripheral smear is done for typing of anaemia. Such evaluation is necessary for
Ingale, Suchita V., Ingale, Vikas C., Ullewar, Milind P., Upadhye, Jayshree J.   +3 more
core   +2 more sources

PERNICIOUS ANEMIA, NUTRITIONAL MACROCYTIC ANEMIA, AND TROPICAL SPRUE [PDF]

Blood, 1948
Abstract The following tentative conclusions as to the relationship of pernicious anemia, nutritional macrocytic anemia and tropical sprue to one another and their pathogenesis are drawn from a study of the literature and from unpublished work: 1.
openaire   +2 more sources