Results 191 to 200 of about 321,908 (256)
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PERNICIOUS ANEMIA IN CHILDHOOD
Archives of Pediatrics & Adolescent Medicine, 1946PERNICIOUS anemia is essentially a disease of adults, 1 rarely seen under the age of 30 and beginning more commonly during the fifth decade. It is characterized by a macrocytic anemia, a related degeneration of the mucosa of parts of the gastrointestinal tract with a resultant complete achlorhydria and frequently a related degeneration of the central ...
Dunn Sc, Peterson Jc
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Pernicious Anemia in Childhood
New England Journal of Medicine, 1965PERNICIOUS anemia in childhood is a rare disorder. Only 25 definitely proved cases have been reported in the medical literature.1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 To establish this diagnosis, other causes of megaloblastic anemia — folic acid deficiency and vitamin B12 deficiency due to a general or specific intestinal absorptive defect — must be
Graham H. Jeffries +3 more
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Hypogammaglobulinemia and Pernicious Anemia
Southern Medical Journal, 1987We have described two patients with pernicious anemia in whom incidental hypogammaglobulinemia was discovered. According to our review of 41 cases of this association reported in the literature, our patients are similar to those previously reported in their young age, the evidence for antral involvement with the atrophic gastritis, and the absence in ...
P E Wright, D A Sears
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Annals of Internal Medicine, 1971
Excerpt To the editor: Although it is commonly stated that pernicious anemia is relatively rarely seen in negroes (1), our clinical impression is that this opinion may be in error.
Paul R. McCurdy, Richard J. Hart
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Excerpt To the editor: Although it is commonly stated that pernicious anemia is relatively rarely seen in negroes (1), our clinical impression is that this opinion may be in error.
Paul R. McCurdy, Richard J. Hart
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New England Journal of Medicine, 1964
THE occasional occurrence of megaloblastic anemia in early childhood was recognized at least thirty years ago, but the relative rarity of cases and the paucity of knowledge of their pathogenesis pr...
Milton S. Sacks +2 more
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THE occasional occurrence of megaloblastic anemia in early childhood was recognized at least thirty years ago, but the relative rarity of cases and the paucity of knowledge of their pathogenesis pr...
Milton S. Sacks +2 more
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2008
Pernicious anemia (PA) is the most common manifestation of vitamin B12 deficiency, in which an autoimmune pathogenesis is supported by (a) the presence of mononuclear-cell infiltration into gastric mucosa with loss of parietal cells, (b) autoantibodies to parietal cells and intrinsic factor, (c) autoreactive T cells, (d) regeneration of parietal cells ...
Alejandro Ruiz-Argüelles +4 more
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Pernicious anemia (PA) is the most common manifestation of vitamin B12 deficiency, in which an autoimmune pathogenesis is supported by (a) the presence of mononuclear-cell infiltration into gastric mucosa with loss of parietal cells, (b) autoantibodies to parietal cells and intrinsic factor, (c) autoreactive T cells, (d) regeneration of parietal cells ...
Alejandro Ruiz-Argüelles +4 more
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Pernicious anemia in childhood
The American Journal of the Medical Sciences, 1978Two children from different families with pernicious anemia are described. The defect appears to be the lack of intrinsic factor in the acid gastric juice. The correct diagnosis and proper therapy are essential for insuring a normal growth and development.
E.Y. Hudaverdi +3 more
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Haptoglobin in Pernicious Anemia
Scandinavian Journal of Clinical and Laboratory Investigation, 1957Haptoglobin (Hp) is a term introduced by Jayk (1939) to designate a group of serum mucaproteins capable of binding hemoglobin stoechiometrically in Vim and in vitro. The haptoglobin content of the serum can be determined by two merhods, both based on the affinity of haptoglobin for hemoglobin.
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Mayo Clinic Proceedings, 1994
We discuss the pathophysiologic mechanisms, clinical features, diagnosis, and treatment of pernicious anemia (PA).A review of the clinical applications of the diagnostic and therapeutic progress of PA is presented.A patient with PA may have a wide range of initial complaints that affect various organ systems or may be entirely asymptomatic. Hematologic
Rajiv K. Pruthi, Ayalew Tefferi
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We discuss the pathophysiologic mechanisms, clinical features, diagnosis, and treatment of pernicious anemia (PA).A review of the clinical applications of the diagnostic and therapeutic progress of PA is presented.A patient with PA may have a wide range of initial complaints that affect various organ systems or may be entirely asymptomatic. Hematologic
Rajiv K. Pruthi, Ayalew Tefferi
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The Nondiagnosis of Pernicious Anemia
Annals of Internal Medicine, 1965Excerpt During the 14-year lifetime of this hospital, 40 patients were admitted with untreated pernicious anemia.
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