Results 41 to 50 of about 10,428 (179)
Functional immune profiling reveals CD4+ T cell dysregulation in coeliac disease
The T cell momentum assay quantifies division, survival and activation decay to reveal intrinsic CD4+ programming defects marked by prolonged activation and impaired feedback control in coeliac disease. This scalable platform provides a functional screen for early T cell dysregulation across autoimmune and immune‐mediated diseases.
Anthony J Farchione +13 more
wiley +1 more source
Well-Differentiated Grade 1 Gastric Neuroendocrine Tumor Occurring 11 Years After Pernicious Anemia [PDF]
Type I gastric neuroendocrine tumors (GNETs) are closely associated with autoimmune atrophic gastritis, particularly pernicious anemia. They arise as a consequence of chronic hypergastrinemia, which induces enterochromaffin- like cell hyperplasia and ...
Aicha CHERIF HOSNI, +5 more
doaj +1 more source
A CASE OF PERNICIOUS ANEMIA [PDF]
In the following case the patient has been under my observation during the past two years, commencing June 21, 1908. The case is a typical one of the severe type and illustrates the remissions which are so characteristic of the condition and also the manner in which the condition for the time being responds to arsenic. Patient.— D.
openaire +1 more source
Higher dietary vitamin B12 intake was inversely associated with the odds of type 2 diabetes mellitus among individuals carrying the TT genotype of the FTO rs9939609 polymorphism. These findings highlight the potential role of precision nutrition strategies in diabetes prevention.
Elham Nikoei Foshtomi +12 more
wiley +1 more source
This post hoc analysis examined the efficacy of ritlecitinib in subgroups of patients with vitiligo, defined by demographic and clinical characteristics. Patients completed the dose‐ranging and extension periods of the phase 2b study (NCT03715829) of ritlecitinib.
A. G. Pandya +8 more
wiley +1 more source
Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis
ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram +5 more
wiley +1 more source
Case Report: Pernicious anemia-associated pancytopenia responds to immunotherapy
Pancytopenia is a life-threatening condition necessitating a prompt, thorough workup to appropriately treat the underlying pathology. We describe a presentation of pancytopenia attributed to myelodysplastic syndrome (MDS)-associated immune-mediated ...
Alexander Krule +4 more
doaj +1 more source
Carcinoïd tumor revealing pernicious anemia
Endocrine tumors (ET) of the digestive tract are rare. Gastric carcinoid was the most common form of gastrointestinal ET's. It is a rare complication of pernicious anemia but may reveal the disease.
Neirouz Ghannouchi Jaafoura +1 more
doaj +1 more source
Unexplained Elevated Vitamin B12: Consider Macro‐B12
ABSTRACT Introduction Elevated vitamin B12 concentration can be caused by supplementation, liver disease, kidney disease, or myeloid malignancies. Persistent, unexplained elevations of vitamin B12 can raise concern among patients and may lead to invasive diagnostic procedures, including bone marrow biopsy.
Evelien G. E. Hurkmans +3 more
wiley +1 more source

