Results 111 to 120 of about 1,053,264 (360)

FAMILIAL NONSPHEROCYTIC HEMOLYTIC ANEMIA [PDF]

, 1950
Eugene Kaplan, Wolf W. Zuelzer
openalex   +1 more source

Energy Deficiency‐Induced ATG4B Nuclear Translocation Inhibits PRMT1‐Mediated DNA Repair and Promotes Leukemia Progression

Advanced Science, EarlyView.
This study demonstrated that ATG4B translocates from the cytoplasm to the nucleus during energy deficiency. Nuclear ATG4B inhibits DNA repair by interacting with PRMT1. The nuclear ATG4B‐mediated DNA repair defect is significantly exacerbated within acute myeloid leukemia (AML) cells, promoting leukemia progression in an AML mouse model.
Zhenkun Wang, Xianli Zhang, Yuanyuan Zhou, Shuyi Lin, Yuting Fu, Haiping Liu, Qiongdan Gao, YanHong Xiao, Zhao Yin, Shuang Liu, Kexiu Huang, Suqi Deng, Juan Du, Hui Zeng, Jia Wang, Jinping Zheng, Qinghua Zhou, Tianfeng Chen, Xiaoling Gao, Zhenyu Ju, Bo Liu   +20 more
wiley   +1 more source

Diagnostic Overlap between Fanconi Anemia and the Cohesinopathies: Roberts Syndrome and Warsaw Breakage Syndrome

Anemia, 2010
Fanconi anemia (FA) is a recessively inherited disease characterized by multiple symptoms including growth retardation, skeletal abnormalities, and bone marrow failure.
Petra van der Lelij, Anneke B. Oostra, Martin A. Rooimans, Hans Joenje, Johan P. de Winter   +4 more
doaj   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source

Refractory Anemia Occurring in Survivors of the Atomic Bombing in Nagasaki, Japan [PDF]

, 1955
Robert D. Lange, Stanley W. Wright, Masanobu Tomonaga, HIROTAMI KURASAKI, SHIGERU MATSUOKE, Haruji Matsunaga   +5 more
openalex   +1 more source

PENYAKIT-PENYAKIT YANG MENYERTAI KEJADIAN KEJANG DEMAM ANAK DI RSUP Dr. KARIADI SEMARANG [PDF]

, 2014
Latar Belakang : Kejang demam dapat dikatagorikan menjadi kejang demam simplek dan kejang demam komplek. Penyakit-penyakit yang menyertai pada kejang demam harus diwaspadai bagi para klinisi karena agar dapat mencegah kerusakan otak yang lebih buruk ...
Nugroho, Wisnu Wahyu, Putranti, Alifiani Hikmah   +1 more
core   +1 more source

RNA G‐Quadruplex RIBOTAC‐Mediated Targeted Degradation of lncRNA TERRA

Advanced Science, EarlyView.
This study introduces a selective RNA degradation strategy targeting long noncoding RNA (lncRNA) TERRA, upregulated in ALT (alternative lengthening of telomeres) cancer cells. Using ribonuclease‐targeting chimeras (RIBOTACs), RNase L is recruited to catalytically degrade TERRA, uncovering a novel approach to affect a disease associated lncRNA in ALT ...
Elias Khaskia, Dipak Dahatonde, Raphael I. Benhamou   +2 more
wiley   +1 more source

Prevalence of Anemia and Iron Deficiency among Palestinian Pregnant Women and Its Association with Pregnancy Outcome

Anemia, 2018
Background. Anemia is a public health problem especially among pregnant women. This study aimed to investigate the prevalence of anemia and iron deficiency among pregnant women and its association with pregnancy outcome in Hebron Governorate in southern ...
Mahmoud A. Srour, Samah S. Aqel, Khaled M. Srour, Khalid R. Younis, Fekri Samarah   +4 more
doaj   +1 more source

A Dual‐Target Recognition System Based on Acid‐Degradable Ni‐MOF and Aptamer Guidance for Precise Tumor Diagnosis and Combined Therapy

Advanced Science, EarlyView.
This work reports a Ni‐doped ZIF‐8 nanoplatform co‐encapsulating glucose oxidase and horseradish peroxidase, enabling a cascade catalytic reaction that produces hydroxyl radicals from endogenous glucose and hydrogen peroxide. Upon near‐infrared irradiation, the system simultaneously achieves photothermal and chemodynamic therapy, offering an effective ...
Jing Xu, Hanxiao Chen, Yifang Tao, Hong Wang, Zhenlong Wang, Yuquan Xue, Delai Fu, Huan Pang, Li Xue   +8 more
wiley   +1 more source

Klippel–Trenaunay syndrome associated with chronic myeloid leukemia

Hematology, Transfusion and Cell Therapy, 2020
C. Coskun, T. Aksu, F. Gumruk, S. Unal
doaj   +1 more source