Results 121 to 130 of about 1,381,466 (410)

Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease [PDF]

, 2012
Background and Aims:We analyzed iron deficiency and the therapeutic response following intravenous ferric carboxymaltose in a large single-center inflammatory bowel disease (IBD) cohort.
Anker SD, Anker SD, Beate Löhr, Breymann C, Burkhard Göke, Carrier J, Chandler G, Cornelia Tillack, De Silva AD, Domenech E, Erichsen K, Erichsen K, Evstatiev R, Fabian Schnitzler, Fleming MD, Fleming RE, Florian Beigel, Ganz T, Gasche C, Gasche C, Julia Seiderer, Katsanos K, Kociol RD, Kulnigg S, Lomer MC, Maria Weidinger, Nemeth E, Nemeth E, Pizzi LT, Qunibi WY, Qunibi WY, Rüdiger P. Laubender, Schroder O, Semrin G, Simone Breiteneicher, Srigiridhar K, Stein J, Stephan Brand, Szczech LA, Tagboto S, Thomas Ochsenkühn, Van Wyck DB, Wells CW, Werner T, Wilson A, Wilson A   +45 more
core   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Dysfunctional telomeres in primary cells from Fanconi anemia FANCD2 patients [PDF]

, 2012
© 2012 Joksic et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium ...
Guc-Scekic, M, Joksic, G, Joksic, I, Leskovac, A, Ojani, M, Petrovic, S, Slijepcevic, P, Stankovic, A, Surralles, J, Trujillo, JP, Vujic, D, Zivkovic, M   +11 more
core   +3 more sources

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Adding eltrombopag to immunosuppression: the importance of predicting outcome

Haematologica, 2021
André Tichelli, Régis Peffault de Latour, Carlo Dufour, Alicia Rovó   +3 more
doaj   +1 more source

Prevalence and Predictors of Maternal Anemia during Pregnancy in Gondar, Northwest Ethiopia: An Institutional Based Cross-Sectional Study

Anemia, 2014
Background. Anaemia is a global public health problem which has an eminence impact on pregnant mother. The aim of this study was to assess the prevalence and predictors of maternal anemia. Method.
Mulugeta Melku, Zelalem Addis, Meseret Alem, Bamlaku Enawgaw   +3 more
doaj   +1 more source

HUBUNGAN IMT, KADAR HAEMOGLOBIN DENGANPRODUKTIVITAS KERJA PADA TENAGA KERJA WANITA [PDF]

, 2005
Sumber daya yang berkualitas merupakan faktor penentu dalam upaya peningkatan produktifitas dalam sebuah perusahaan. Anamia merupakan masalah kesehatan masyarakatyang serius karena berdampak pada perkembangan fisik dan psikis, perilaku dan kerja.
NOVITASARI, DEWI
core  

The Evolving Pharmacotherapeutic Landscape for the Treatment of Sickle Cell Disease. [PDF]

, 2020
Sickle cell disease (SCD) is an extremely heterogeneous disease that has been associated with global morbidity and early mortality. More effective and inexpensive therapies are needed.
Ballas, Samir K
core   +1 more source

Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up [PDF]

, 2016
Primary autoimmune hemolytic anemia (P-AIHA) is a relatively uncommon and hetereogeneous disease characterized by the destruction of red blood cells due to anti-erythrocyte autoantibodies (AeAbs) in the absence of an associated disease [1–3].
ARMIENTO, DANIELE, CARONNA, Roberto, COLAFIGLI, GIOIA, Coluzzi, S, De Propris, Ms, FERRETTI, ANTONIETTA, FOA, Roberto, GIOVANNETTI, GIANLUCA, GIRELLI, Gabriella, GUARINI, Anna, LA ROCCA, URSULA, MAURO, Francesca Romana, MOLICA, MATTEO, Morano, G, Paoloni, F, Trastulli, F   +15 more
core   +1 more source

TREATING ANEMIA

Hematology/Oncology Clinics of North America, 1996
Transfusion therapy is frequently used in the treatment of sickle cell disease and its complications, but its efficacy has not been well proven. Red cell transfusions are well established for the acute treatment of cerebrovascular accidents and for the prevention of their recurrence.
K E, King, P M, Ness
openaire   +2 more sources