Results 261 to 270 of about 1,381,466 (410)

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Predictors of anemia among lactating women in ethiopia: Using 2016 EDHS; application of ordinal logistic regression model. [PDF]

Sci Rep
Tsegaye TG, Azeze GA, Negash BT.
europepmc   +1 more source

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Evaluating the Effectiveness of Early Genetic Screening for Fanconi Anemia in High-Risk Pediatric Populations. [PDF]

Mol Genet Genomic Med
Al-Doski AAS.
europepmc   +1 more source

Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia

New England Journal of Medicine, 2017
D. Townsley, P. Scheinberg, T. Winkler, R. Desmond, B. Dumitriu, O. Rios, B. Weinstein, Janet Valdez, J. Lotter, Xingmin Feng, M. Desierto, Harshraj Leuva, M. Bevans, Colin O. Wu, A. Larochelle, K. Calvo, C. Dunbar, N. Young   +17 more
semanticscholar   +1 more source

Clinical Images: Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome presenting as aseptic pustular dermatosis: A rare clinical manifestation

Arthritis &Rheumatology, EarlyView.
Peter Chen, Héloïse Briançon, Deborah Eshagh, Tali‐Anne Szwebel, Benjamin Terrier, Pierre Sohier, Rudy Birsen   +6 more
wiley   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Aplastic anemia successfully treated with rituximab: the possible role of aplastic anemia-associated autoantibodies as a marker for response

, 2011
Hiroyuki Takamatsu, Hiroshi Yagasaki, Yoshiyuki Takahashi, Asahito Hama, Yutaka Saikawa, Akihiro Yachie, Shoichi Koizumi, Seiji Kojima, Shinji Nakao   +8 more
openalex   +2 more sources

An automated microfluidic biosensor with bispecific rabbit monoclonal antibody and nanozyme‐bioenzyme composite for dual antibiotic detection

BMEMat, EarlyView.
This study introduces an automated microfluidic biosensor for simultaneous detection of florfenicol and thiamphenicol in environmental water. By integrating a phage‐screened bispecific rabbit monoclonal antibody with a nanozyme‐bioenzyme composite, the system achieves sensitive dual‐antibiotic detection. Coupled with smartphone‐based sensing, it offers
Fuyuan Zhang, Yang Liu, Juntao Wang, Haichao Zhang, Wenlong Yu, Yaxin Sang, Yun Liu, Guangze Yang, Fang Gao, Shuo Wang, Shilun Feng, Xianghong Wang   +11 more
wiley   +1 more source

Sickle Cell Disease: Genetics, Cellular and Molecular Mechanisms, and Therapies

Anemia, 2012
Betty S. Pace, Solomon F. Ofori-Acquah, Kenneth R. Peterson   +2 more
doaj   +1 more source