Results 31 to 40 of about 757,181 (341)

A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum

Haematologica, 2013
Hemojuvelin is a critical regulator of hepcidin expression and can be cleaved by proteases to form soluble hemojuvelin. Soluble hemojuvelin has been recently identified in human serum but the presence and quantity of soluble hemojuvelin in mouse serum is
Wenjie Chen, Chia Chi Sun, Shanzhuo Chen, Delphine Meynard, Jodie L. Babitt, Herbert Y. Lin   +5 more
doaj   +1 more source

Correction of anemia with epoetin alfa in chronic kidney disease.

New England Journal of Medicine, 2006
BACKGROUND Anemia, a common complication of chronic kidney disease, usually develops as a consequence of erythropoietin deficiency. Recombinant human erythropoietin (epoetin alfa) is indicated for the correction of anemia associated with this condition ...
Ajay K. Singh, L. Szczech, K. Tang, H. Barnhart, Shelly Sapp, M. Wolfson, D. Reddan   +6 more
semanticscholar   +1 more source

Sickle Cell Anemia: Variants in the CYP2D6, CAT, and SLC14A1 Genes Are Associated With Improved Hydroxyurea Response

Frontiers in Pharmacology, 2020
Differences in hydroxyurea response in sickle cell anemia may arise due to a series of factors with genetic factors appearing to be predominant. This study aims to investigate the effects of single nucleotide polymorphisms in genes encoding drug ...
Sètondji Cocou Modeste Alexandre Yahouédéhou, Sètondji Cocou Modeste Alexandre Yahouédéhou, Joelma Santana dos Santos Neres, Caroline Conceição da Guarda, Caroline Conceição da Guarda, Suellen Pinheiro Carvalho, Suellen Pinheiro Carvalho, Rayra Pereira Santiago, Rayra Pereira Santiago, Camylla Vilas Boas Figueiredo, Camylla Vilas Boas Figueiredo, Luciana Magalhães Fiuza, Luciana Magalhães Fiuza, Uche Samuel Ndidi, Rodrigo Mota de Oliveira, Rodrigo Mota de Oliveira, Cleverson Alves Fonseca, Valma Maria Lopes Nascimento, Larissa Carneiro Rocha, Corynne Stéphanie Ahouéfa Adanho, Tiago Santos Carvalho da Rocha, Elisângela Vitória Adorno, Marilda Souza Goncalves, Marilda Souza Goncalves   +23 more
doaj   +1 more source

Knowledge of Intestinal Parasitic Infection and Anemia among Pregnant Women Attending Antenatal Clinic in Ogun State

International Journal of Innovative Science and Research Technology
A study was conducted at General Hospital Ijebu Igbo antenatal section to investigate the prevalence of intestinal parasitic infection and anemia in pregnant women.
Oluwabiyi, A. Bolatito, Akanbi, O. Hannah, Oluwaseun Ipede   +2 more
semanticscholar   +1 more source

Anemias. [PDF]

JAMA: The Journal of the American Medical Association, 1898
n ...
openaire   +1 more source

Global, Regional, and National Prevalence of Anemia and Its Causes in 204 Countries and Territories, 1990–2019

Current Developments in Nutrition, 2020
To estimate the total prevalence of anemia by severity and quantify the contribution attributable to 35 underlying causes for 204 countries and territories by age and sex from 1990 to 2019.
W. Gardner, N. Kassebaum
semanticscholar   +1 more source

A systematic analysis of global anemia burden from 1990 to 2010.

Blood, 2014
Previous studies of anemia epidemiology have been geographically limited with little detail about severity or etiology. Using publicly available data, we estimated mild, moderate, and severe anemia from 1990 to 2010 for 187 countries, both sexes, and 20 ...
N. Kassebaum, Rashmi Jasrasaria, M. Naghavi, S. Wulf, N. Johns, R. Lozano, M. Regan, D. Weatherall, David P Chou, T. Eisele, S. Flaxman, R. Pullan, S. Brooker, C. Murray   +13 more
semanticscholar   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

The Fanconi Anemia Pathway in Cancer.

Annual Review of Cancer Biology, 2019
Fanconi anemia (FA) is a complex genetic disorder characterized by bone marrow failure (BMF), congenital defects, inability to repair DNA interstrand cross-links (ICLs), and cancer predisposition.
Joshi Niraj, A. Färkkilä, A. D’Andrea   +2 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source