Results 121 to 130 of about 491,112 (258)

Parvovirus B19 Infection in Pregnancy—Course of the Disease, Fetal Complications and Management Tools: A Case Series and Literature Review

Children
Parvovirus B19 is a virus that causes a common and usually harmless infection in both children and adults. If the virus is transmitted transplacentally during pregnancy, it can have serious consequences for both the pregnant woman and the fetus ...
Olga Olejniczak, Jakub Kornacki, Daniel Boroń, Paweł Gutaj, Rafał Iciek, Ewa Wender-Ożegowska   +5 more
doaj   +1 more source

The non-homologous end-joining activity is required for Fanconi anemia fetal HSC maintenance. [PDF]

Stem Cell Res Ther, 2019
Nie Y, Li Y, Li X, Wilson AF, Pang Q.
europepmc   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Sixth-Month Perinatal Outcomes of Anemic Pregnancies

Gynecology Obstetrics & Reproductive Medicine, 2014
OBJECTIVE: In this study, we retrospectively compare the outcomes of anemia in 3rd trimester pregnant women who applied to our clinic, in terms of maternal factors and its fetal effects, in 0 and 6th months.
Emel Kıyak Çağlayan, Öznur Küçük, Ayşe Yeşim Göçmen, Levent Seçkin, Ayla Aktulay, Yaprak Engin Üstün   +5 more
doaj  

Neuroimaging Findings and Risk Factors for Brain Injury in Foetuses Treated for Anaemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Characterize neuroimaging findings in foetuses with anaemia and identify associated risk factors. Methods Retrospective cohort study of pregnancies with foetal anaemia (defined as haemoglobin > 2 standard deviations below the gestational age mean) confirmed by foetal blood sampling (FBS) and treated with intrauterine transfusion (IUT)
Laurence Sophie Carmant, Carlos Robles, Seungwoo Lee, Prakesh S. Shah, Greg Ryan, Elka Miller, Shiri Shinar   +6 more
wiley   +1 more source

Transfusión fetal intrauterina en anemia fetal severa: a propósito de un caso

Este articulo trata del caso clínico presentado sobre la transfusión fetal intrauterina en anemia fetal severa. La anemia fetal es una afección poco común pero que puede provocar una morbilidad y mortalidad perinatal significativa si no se diagnostica y
Moreno Lombardi, Pilar, Vargas Valdivia, Víctor, López Baltra, Ignacia, Estefane Durán, Andrés, Maldonado Kopaitic, Josefina   +4 more
core  

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source