Results 171 to 180 of about 68,904 (262)

Comparison of four different in vitro assays for prediction of potential RBC antibody clinical significance

Transfusion, EarlyView.
Abstract Background The monocyte monolayer assay (MMA) uses monocytes, but it is known that antibody‐mediated hemolysis occurs in macrophages. Whether the use of macrophages would improve the predictive capacity of the MMA is unclear. Also, it is unclear if RBC alloantibodies contribute to hemolysis via antibody‐dependent cellular cytotoxicity (ADCC ...
Yeniley Ruiz Noa, Clémence Salou, Myriam Beshai, Selena Y. Cen, Lindsay K. Hillis, Katrina Billingsley, Donald R. Branch   +6 more
wiley   +1 more source

Identification of Novel Therapeutic Agent Candidates Through High Throughput Screening With Chemical Library Based on Molecular Subclassification in Canine Histiocytic Sarcoma Cell Lines

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Effective chemotherapy for canine histiocytic sarcoma (CHS) has yet to be established. In our previous study, CHS cell lines were subclassified into two groups based on their gene expression profiles: Group A and Group B. This study aimed to identify novel therapeutic agents that are effective against each CHS subgroup, and we performed high ...
Hiroki Sakuma, Hirotaka Tomiyasu, Mari Takamiya, Yuko Goto‐Koshino, Atsushi Tsukamoto, Makoto Bonkobara, Masaru Okuda   +6 more
wiley   +1 more source

Placental Evidence of Intrauterine Stress: Mechanisms, Timing, and Links to Perinatal Brain Injury. [PDF]

J Clin Med
Kim CF, Carreon CK.
europepmc   +1 more source

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions

The Journal of Physiology, EarlyView.
Abstract figure legend ACE I/D genotype, enzyme activity and integrated physiological adaptations. Upper panel: Conceptual framework linking the ACE I/D polymorphism (left) with circulating/tissue ACE activity (centre; violin plots based on hypothetical data for illustration) and strength/power versus endurance phenotypes (right).
Tórur Sjúrðarson, Nikolai B. Nordsborg   +1 more
wiley   +1 more source

Monopolar Single Tip Radiofrequency as Treatment of Giant Placental Chorioangioma. [PDF]

Prenat Diagn
Dumery G, Megier C, Luton D, Baron X, Dhombres F, Joseph Vivanti A, Maurice P.   +6 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

Diagnosis and management of mirror syndrome: a case series with emphasis on the potential role of the sFLT-1/PlGF ratio in clinical practice. [PDF]

Rev Bras Ginecol Obstet
Behenck GS, Curtois F, El Beitune P, Jimenez MF, Vettorazzi J, da Silva MB, Muller B, Teixeira L, Longo C, Callado GY, Araujo Júnior E, Micheletti T.   +11 more
europepmc   +1 more source

Pathomechanism of Fever‐Induced Liver Failure in NBAS Deficiency and Treatment Effect of NAC—Observations In Vitro and In Vivo

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Pathogenic variants in neuroblastoma amplified sequence (NBAS) gene causes infantile liver failure type 2 (IFLS2; MIM 616483), characterised by recurrent episodes of liver failure triggered by febrile infections. The underlying pathophysiological mechanisms remain incompletely understood. With this work we try to shed light
Tian Sun, Nicole Hammann, Lina Leghlam, Bianca Peters, Cigdem Arikan, Sarah M. Bedoyan, Qian Chen, Tal Dattner, Felix Distelmaier, Alexander Fichtner, Sven F. Garbade, Nedim Hadžić, Robert Hegarty, Andrea Hellwig, Marianne Hørby Jørgensen, Carolin Jentsch, Sabine Jung‐Klawitter, Martin Laass, Elke Lainka, Hannah Münch, Halise Neslihan Önenli Mungan, Moritz Niesert, Stephanie Oehrl, Begona Polo, Knut Schäkel, James E. Squires, Stefan Kölker, Georg F. Hoffmann, Christian Staufner, Dominic Lenz   +29 more
wiley   +1 more source

Could excessive zinc supplementation during pregnancy cause menkes disease? A hypothesis worth investigating. [PDF]

Front Pediatr
Mugundan UM, Saravanan V, Rajanandh MG.
europepmc   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source