Results 91 to 100 of about 38,202 (259)

Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models

Andrology, EarlyView.
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao, Xi Zhang, Lingru Li, Yunzhi Zhang, Shuo Huang, Yulin Zong, Mingrui Li, Fufangyu Zhao, Linghui Zhu, Tianxing Li, Wenlong Sun, Mingyan Shao, Yanfei Zheng   +12 more
wiley   +1 more source

Comparative study of blood biochemistry in clinically healthy farmed barramundi (Lates calcarifer) and rainbow trout (Oncorhynchus mykiss) from freshwater recirculating aquaculture systems

Australian Veterinary Journal, EarlyView.
Barramundi (Lates calcarifer) is an economically significant aquaculture species and ranks among Australia's top five farmed finfish. As global production intensifies, understanding the physiology and health of barramundi is essential to support animal welfare and industry profitability.
CY(V) Pang, N Courtman, F Samsing
wiley   +1 more source

Pediatric Regional Anesthesia Survey in South Africa (PRASSA): A Descriptive, Cross‐Sectional Survey of Knowledge, Attitudes, and Practices Among South African Anesthetists

Pediatric Anesthesia, EarlyView.
Shauneen Kelber, Alexandra Torborg, Hyla‐Louise Kluyts   +2 more
wiley   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Design for a Reusable High‐Fidelity Pediatric Epidural and Caudal Phantom for Haptic Learning

Pediatric Anesthesia, EarlyView.
Rani A. Sunder, Huy Le
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

Vesicular glutamate transporter VGLUT2 expression emerges in substantia nigra dopamine neurons in mouse models of parkinsonism in the absence of neurodegeneration

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Subsets of midbrain dopamine (DA) neurons express the vesicular glutamate transporter VGLUT2 and can release the excitatory neurotransmitter glutamate. VGLUT2+ DA neurons of the substantia nigra pars compacta (SNc) were shown to be more resistant to neurodegeneration in animal models of Parkinson's disease (PD ...
Sivakumar Srinivasan, Christian Pifl, Thomas Steinkellner   +2 more
wiley   +1 more source

Platelet‐Rich Fibrin Can Improve Septoplasty Results: A Prospective Randomised Controlled Trial

Clinical Otolaryngology, EarlyView.
ABSTRACT Aim This study aims to assess the impact of platelet‐rich fibrin (PRF) on nasal mucociliary clearance (NMC) time and post‐operative pain following septoplasty. Patients and Methods This trial was conducted involving patients who underwent septoplasty. Participants were randomly assigned to either a control group or a PRF group.
Emre Solguntekin, Sedat Çağlı, Kerem Kökoğlu, Emrah Gülmez   +3 more
wiley   +1 more source

Evidence‐ and consensus‐based guideline on lichen sclerosus

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The German‐language, consensus‐ and evidence‐based S3 guideline on lichen sclerosus (LS) was developed based on the European “EuroGuiDerm Guideline on lichen sclerosus” under the leadership of the German Dermatological Society (DDG) and the German Society for Gynecology and Obstetrics (DGGG).
Gudula Kirtschig, Linn Woelber, Andreas Günthert, Karl Becker, Alexandra Ciresa‐König, Bettina Fischer, Susanne Fricke‐Otto, Claudia Günther, Christine Hirchenhain, Narayani Helga Köllmann, Alexander Kreuter, Bartosz Malisiewicz, Felix Neis, Dan mon O'Dey, Hagen Ott, Martin Promm, Regina Renner, Anne‐Rose Schardt, Ines Schweizer, Raimund Stein, Jan Ter‐Nedden, Gerda Trutnovsky, Agnes Wand, Gerhard Weyandt, Ricardo N. Werner, Maria Kinberger   +25 more
wiley   +1 more source