Results 141 to 150 of about 535,348 (302)

Multivalent Bi‐Specific Nanoerythrosomes: A Two‐Birds‐One‐Stone Approach to Combine Homologous and Active Targeting for Effective Thrombolysis

Small, EarlyView.
A multivalent bi‐specific nanoerythrosome (mBiNE@tPA) is developed as a “two‐birds‐one‐stone” platform that simultaneously exploits two principal thrombus components. By integrating erythrocyte membrane‐mediated homologous targeting with cRGD‐based active targeting to activated platelets, mBiNE@tPA achieves enhanced thrombus accumulation, triggered ...
Yu Huang, Yilin Yang, Nicole Henry, Boram Gu, Jiahua Wang, Yuanyuan Guo, Colin Longstaff, Simon A. Thom, Yuehua Li, Xiao Yun Xu, Rongjun Chen   +10 more
wiley   +1 more source

Ultrasound-Guided Caudal Epidural Block Versus Saddle Block for Anorectal Surgeries: A Prospective Randomized Comparative Study. [PDF]

Cureus
Rajendran I, Vadhanan P, Ampalaya MR, Priyadharshini P.   +3 more
europepmc   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Prone Position and Epidural Anesthesia Without Secured Airway: Prospective Case Study in Infants Undergoing Surgery for Anorectal Malformations. [PDF]

J Clin Med
Zeilberger M, Marhofer P, Zadrazil M, Opfermann P, Fartacek R, Schmid W.   +5 more
europepmc   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

UroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson, William Brenseke, Diego Alvarez Vega, William Nguyen, Mohammed Shium, Saige Gitlin, Ronnie G. Fine, Steven C. Friedman, Mark Horowitz, Walter I. Weiss, Raghu Idupuganti, Jordan S. Gitlin   +11 more
wiley   +1 more source

Predicting Sensory Block Level in Caudal Anesthesia Based on Sacral Canal Anatomical Parameters and Height: Development of an Ordinal Logistic Regression Model and Nomogram. [PDF]

Ther Clin Risk Manag
Li Z, Wu H, Zhang S, Yu S, Liu L, Liufu N.   +5 more
europepmc   +1 more source

Causes, treatment and outcome of external ear canal tears and avulsions in cats and dogs: 24 cases (2008‒2024)

Veterinary Record, EarlyView.
Abstract Background This study aimed to evaluate the causes, treatment options and associated complications of ear canal tears and avulsions in dogs and cats. Methods This retrospective clinical study includes 14 cats and 10 dogs diagnosed with external ear canal tears and avulsions using otoscopy and/or computed tomography.
Eva M. Billau, Cetina Thiel
wiley   +1 more source

Thrombocytosis and tumour distribution predict outcome in dogs with hepatocellular carcinoma: A multi‐institutional retrospective analysis

Veterinary Record, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is the most common canine hepatobiliary tumour. This study aimed to determine which criteria influenced outcome of HCC in a modern population of dogs across eight institutions. Methods The medical records of 106 dogs with HCC were retrospectively reviewed.
Emily A. Janik, MacKenzie A. Pellin, Dawn M. Clarke   +2 more
wiley   +1 more source

Effect of caudal block injection speed on optic nerve sheath diameter in pediatric surgeries: A prospective observational cohort study. [PDF]

Medicine (Baltimore)
Toprak Karaoğlu A, Karaoğlu RO, Özen V.   +2 more
europepmc   +1 more source

Vaginal Hysterectomy Versus Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery Hysterectomy; Results of a Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare Vaginal Hysterectomy (VH) with Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery (NOTES) hysterectomy (VANH) as a day‐care procedure. Design Single‐blind, multicentre randomised controlled trial. Setting Two Dutch non‐academic teaching hospitals.
Ilse P. W. Bekkers, Floor R. M. Wintraecken, Nicol A. C. Smeets, Anne Damoiseaux, Jacques W. M. Maas, Huib A. A. M. van Vliet, Martine M. L. H. Wassen   +6 more
wiley   +1 more source