General anesthesia reduces complexity and temporal asymmetry of the informational structures derived from neural recordings in Drosophila [PDF]
We apply techniques from the field of computational mechanics to evaluate the statistical complexity of neural recording data from fruit flies. First, we connect statistical complexity to the flies' level of conscious arousal, which is manipulated by general anesthesia (isoflurane).
arxiv +1 more source
Modified mylohyoid anesthesia with 4% articaine and with adrenaline and dexasamethasone in mandibular molar surgery: A pilot study [PDF]
Introduction: Mylohyoid mandibular anesthesia is not a standard and independent primary anesthesia for performing surgery on mandibular teeth. Objective: The objective was to examine the success of achieved mylohyoid anesthesia for mandibular molar ...
Burić Kristina N.+4 more
doaj +1 more source
Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy. [PDF]
Myotonic dystrophy type I (DM1) exhibits distinctive disease specific phenotypes and the accelerated onset of a spectrum of age-associated pathologies.
Abdallah, Walid F+9 more
core +1 more source
Towards Real-World Applications of Personalized Anesthesia Using Policy Constraint Q Learning for Propofol Infusion Control [PDF]
Automated anesthesia promises to enable more precise and personalized anesthetic administration and free anesthesiologists from repetitive tasks, allowing them to focus on the most critical aspects of a patient's surgical care. Current research has typically focused on creating simulated environments from which agents can learn.
arxiv +1 more source
The Role of Locoregional Anesthesia in the Covid-19 Pandemic
Coronavirus disease 2019 (COVID-19) refers to the respiratory tract infection caused by the newly emergent coronavirus SARS-CoV-2. The present pandemic, declared on the 11th of March 2020, was first recognized in Wuhan city, and rapidly spread ...
Ângela Barbosa Mendes+5 more
doaj +1 more source
Postoperative atrial fibrillation: The role of the inflammatory response [PDF]
OBJECTIVE: Abnormal atrial conduction has been shown to be a substrate for postoperative atrial fibrillation (POAF). This study aimed to determine the relationship between the location of the atrial reentry responsible for POAF, and degree of atrial ...
Damiano, Ralph J+4 more
core +2 more sources
A Model-Based Architecture for Automatic Anesthesia Infusion [PDF]
This paper presents a model-based control architecture. Based on the Medical Cyber-physical Systems (MCPS) concept, we construct a safe and reliable automatic anesthesia control closed-loop system. The control architecture uses the patient's propofol pharmacokinetic/pharmacodynamic model, using the calculated results as a feedback signal to correct the
arxiv
The thermodynamics of general anesthesia [PDF]
It is known that the action of general anesthetics is proportional to their partition coefficient in lipid membranes (Meyer-Overton rule). This solubility is, however, directly related to the depression of the temperature of the melting transition found close to body temperature in biomembranes. We propose a thermodynamic extension of the Meyer-Overton
arxiv +1 more source
Radical pairs may play a role in xenon-induced general anesthesia [PDF]
Understanding the mechanisms underlying general anesthesia would be a key step towards understanding consciousness. The process of xenon-induced general anesthesia has been shown to involve electron transfer, and the potency of xenon as a general anesthetic exhibits isotopic dependence. We propose that these observations can be explained by a mechanism
arxiv +1 more source
To date, much research has focused on finding the ideal adjuvant for local anesthetics. Each of them can have different effects. In anesthesiology and pain medicine, depending on the purpose, one or another effect may be desirable.
Dmytro Dmytriiev+2 more
doaj +1 more source