Results 101 to 110 of about 66,937 (306)

Horizontal gaze palsy following intraoral local anesthesia, a first manifestation of multiple sclerosis

open access: yesRevista Mexicana de Oftalmología, 2017
Introduction: Different type of anesthesia has been implicated in the exacerbation of multiple sclerosis. Moreover, dental anesthesia is related to ophthalmologic complications such as diplopia due to oculomotor nerves palsy.
Vanesa Rivero-Gutiérrez   +2 more
doaj   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

open access: yesAdvanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen   +11 more
wiley   +1 more source

Dental local anesthetic injection simulation in dental anesthetic education : Educational effects in applying simulation models in clinical training [PDF]

open access: yes, 2002
P(論文)In clinical training sessions at the Dental Anesthesia course (5th year dental school), interactive training involving dental local anesthetic injection is conducted.
37591   +11 more
core   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba   +25 more
wiley   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

Dental Treatments Under General Anesthesia Over The Last 10 Years

open access: yesInternational Dental Journal
Aim or purpose: This study analyzed dental treatments under general anesthesia at the Department of Pediatric Dentistry of ‘A’ National University Dental Hospital from 2014 to 2023.
Yuri Jeong   +4 more
doaj   +1 more source

Management of hyperthyroid patients in dental emergencies: a case report [PDF]

open access: yes, 2016
The prevalence of thyroid disease, particularly hyperthyroidism, has rapidly increased in Korea in the past 10 years. Therefore, it is important to consider the complete medical history including thyroid disease in patients under dental treatment.
곽은정   +5 more
core   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li   +13 more
wiley   +1 more source

CXCL10/SLC11A1 Axis Exacerbates Septic Liver Injury by Regulating Neutrophil Extracellular Traps Formation to Drive Macrophage Pro‑Inflammatory Polarization

open access: yesAdvanced Science, EarlyView.
In sepsis‐induced liver injury, marked neutrophil infiltration correlates with disease severity. Neutrophil SLC11A1 drives intracellular Fe2+ and ROS via the Fenton reaction, promoting NETs formation. Hepatocyte‐derived CXCL10 recruits neutrophils and activates the JAK/STAT1/SLC11A1 axis, enhancing NETs‐mediated inflammation.
Haiping Lin   +8 more
wiley   +1 more source

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