Results 131 to 140 of about 101,461 (316)

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

TRICHLORETHYLENE IN DENTAL ANESTHESIA [PDF]

Southern Medical Journal, 1944
openaire   +2 more sources

High‐Density Flexible Neural Implants with Submicron Feedline Resolution

Advanced Electronic Materials, EarlyView.
Optimization of microfabrication methods using optical contact lithography (OCL) and electron beam lithography (EBL) enables the fabrication of 64‐channel, high‐density, parylene‐C‐based intracortical implants with submicron feedlines as narrow as 400 and 50 nm, respectively.
Lina Koschinski, Thomas Grap, Erkan Yilmaz, Marius Kleutgens, Simon Decke, Martin Kasavetov, Marie Jung, Alejandro Carnicer‐Lombarte, George Malliaras, Andreas Offenhäusser, Viviana Rincón Montes   +10 more
wiley   +1 more source

IKIMOKYKLINIO AMŽIAUS VAIKŲ TĖVŲ ŽINIOS APIE DANTŲ GYDYMĄ SEDACIJOS IR BENDROSIOS NEJAUTROS ATVEJU BEI BURNOS PRIEŽIŪRĄ = PARENTS KNOWLEDGE ABOUT PRESCHOOL CHILDREN DENTAL TREATMENT UNDER SEDATION AND GENERAL ANESTHESIA AND MOUTH CARE

Taikomieji tyrimai studijose ir praktikoje, 2019
Sedation and general anesthesia are based on pharmacological treatment of child behaviour. The main purpose of sedation and general anesthesia processes is the management of children's behaviour and pain control.
Rima Adomaitienė, Angelina Naskauskienė   +1 more
doaj  

Incidence of traumatic dental injuries associated with orotracheal intubation in general anesthesia in children during mixed dentition in Damascus, Syria: a prospective longitudinal study

BDJ Open
Objectives Endotracheal tube intubation by laryngoscope during general anesthesia is a safe procedure with a few complications. However, it may cause some damage to the oral cavity structures, which leads to postoperative pain and discomfort.
Mohammed N. Al-Shiekh, Mohamed Altinawi, Bana Darwish, Mawia Karkoutly   +3 more
doaj   +1 more source

Multifunctional Framework Nucleic Acid Vehicle for Antibiotic Sensitization and Treatment of Methicillin‐Resistant Staphylococcus aureus

Aggregate, EarlyView.
A self‐assembling, aggregation‐enhanced tetrahedral DNA nanostructure (tFNA), termed TACs, enables localized accumulation and sustained release of ceftriaxone while co‐delivering antisense oligonucleotides that silence mecA, reduce PBP2a expression, and restore β‐lactam susceptibility in MRSA.
Yicheng Zhao, Jingyi Si, Shisong Jing, Bingmei Wang, Yueshan Xu, Jiyu Guan, Quan Liu, Jianlei Shen, Min Lv, Li Wang, Changfeng Zhu   +10 more
wiley   +1 more source

Selenium‐Containing Polyurethane Thermo‐Sensitive Hydrogel Accelerates Diabetic Wound Healing by Activating Unfolded Protein Response

Aggregate, EarlyView.
The selenium‐containing polyurethane (SePU) thermo‐sensitive hydrogel (SePU/HBC) was constructed by incorporating SePU into hydroxybutyl chitosan (HBC). This hydrogel alleviates endoplasmic reticulum stress (ERS) and inhibits cell apoptosis by activating the unfolded protein response (UPR), thereby promoting diabetic wound healing.
Mo Zhai, Zilun Huang, Banruo Xianyu, Xiaoqiang Bai, Zhuqing Wan, Yang Fu, Huaping Xu, Longwei Lv, Yongsheng Zhou   +8 more
wiley   +1 more source

Lung‐Penetrating Biomimetic Extracellular Vesicle Spherical Nucleic Acids for Pulmonary Fibrosis Therapy Through ROS Scavenging and Anti‐Inflammatory Effects

Aggregate, EarlyView.
This work describes a biomimetic extracellular vesicle‐spherical nucleic acid (BEV‐SNA) platform for idiopathic pulmonary fibrosis (IPF) therapy. BEV‐SNA is composed of mechanically extruded BEVs from primary MSCs and cholesterol‐modified ssDNA that are assembled through hydrophobic interactions.
Saiyun Lou, Jiangpo Ma, Pan Fu, Lin Li, Jingyun Huang, Fangxue Jing, Yuhui Wang, Sihua Qian, Jianping Zheng, Jiang Li, Zhaoxing Dong, Kaizhe Wang   +11 more
wiley   +1 more source

Consideration for care for your patient with cerebral palsy [PDF]

, 2018
Cerebral palsy (CP) is a common developmental neurological disorder affecting about 2-3 children out of 1,000. CP is the result of infant brain damage or abnormal development resulting in impaired muscle control, coordination, tone, reflex, posture, and ...
Cannon, Katlin R, Ryan, Brooke, Stowe, Melissa   +2 more
core   +1 more source

Addressing Anemia in High‐Altitude Populations: Global Impact, Prevalence, Challenges, and Potential Solutions

American Journal of Hematology, EarlyView.
Key challenges in diagnosing anemia in high‐altitude populations include variability in hemoglobin (Hb) concentration, associated pathological conditions, altitude‐induced plasma volume changes, and environmental factors such as contamination and nutrition.
Ayoub Boulares, Nicola Luigi Bragazzi, Gustavo F. Gonzales, Paul Robach, Benoit Champigneulle, Julien V. Brugniaux, Emeric Stauffer, Elie Nader, Stéphane Doutreleau, Philippe Connes, Samuel Verges, Aurélien Pichon   +11 more
wiley   +1 more source