Results 191 to 200 of about 54,521 (292)

Polypharmacy with tiagabine, levetiracetam, and perampanel in status epilepticus: Insights from EEG, biochemical, and histopathological studies in rats

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Status epilepticus (SE) is a condition of neurological emergency, which precipitates various functional and morphological changes in the brain. Due to the risk of drug resistance associated with SE, this study aimed to evaluate a multitargeted approach to treat SE by combining clinically used antiseizure drugs. Methods In this study,
Sana Javaid   +7 more
wiley   +1 more source

Education regarding opioid prescription within oral and maxillofacial surgery residency programs: a survey study. [PDF]

open access: yesJ Dent Anesth Pain Med
Beals DW   +5 more
europepmc   +1 more source

Calpastatin, a calpain specific inhibitor, reduce seizures in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy is a chronic condition characterized by unpredictable and recurrent spontaneous seizures. In a previous study, we reported that pharmacological inhibition of calpain prevented epileptogenesis in the rat pilocarpine model. In this study, we demonstrate that transgenic overexpression of calpastatin, the endogenous inhibitor of calpain ...
Philip M. Lam   +3 more
wiley   +1 more source

Cardiac structural and molecular alterations in rodent models of temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cardiac structural and molecular changes are prevalent in people with chronic epilepsy, possibly contributing to an increased risk of premature mortality. However, understanding of the underlying pathophysiological mechanisms is limited.
Zining Liu   +9 more
wiley   +1 more source

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

open access: yesFood Frontiers, EarlyView.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno   +17 more
wiley   +1 more source

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